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1.060 Aktuelle Fachpublikationen in Nature Medicine

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Cancer: Risky Y chromosome loss

05.06.2014 | Hannah Stower, Nature Medicine, 2014

Nature Medicine 20, 594 (2014). doi:10.1038/nm.3601 Author: Hannah Stower

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An alternative DNA damage pathway to apoptosis in hematological cancers

05.06.2014 | John M Luk; Kun-Liang Guan, Nature Medicine, 2014

Nature Medicine 20, 587 (2014). doi:10.1038/nm.3593 Authors: John M Luk & Kun-Liang Guan Although hematological cancers are genomically unstable, the mechanisms by which they evade DNA damage–induced cell death are largely unknown. A current study has revealed that the Hippo ...

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Overcoming Drug Development Bottlenecks With Repurposing: Repurposing biguanides to target energy metabolism for cancer treatment

05.06.2014 | Michael Pollak, Nature Medicine, 2014

Nature Medicine 20, 591 (2014). doi:10.1038/nm.3596 Author: Michael Pollak

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Cardiomyopathy, mitochondria and Barth syndrome: iPSCs reveal a connection

05.06.2014 | Kunil K Raval; Timothy J Kamp, Nature Medicine, 2014

Nature Medicine 20, 585 (2014). doi:10.1038/nm.3592 Authors: Kunil K Raval & Timothy J Kamp Barth syndrome is a rare X-linked genetic disorder caused by mutations in the tafazzin (TAZ) gene that result in dilated cardiomyopathy, skeletal myopathy and neutropenia. Tafazzin has a ...

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Cardiac hypertrophy: A miRNA star in the heart

05.06.2014 | Michael Basson, Nature Medicine, 2014

Nature Medicine 20, 595 (2014). doi:10.1038/nm.3604 Author: Michael Basson

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Neuronal development: Environmental brain protection

05.06.2014 | Eva Chmielnicki, Nature Medicine, 2014

Nature Medicine 20, 595 (2014). doi:10.1038/nm.3606 Author: Eva Chmielnicki

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Interleukin-35 takes the 'B' line

05.06.2014 | Claudia Mauri; Kiran Nistala, Nature Medicine, 2014

Nature Medicine 20, 580 (2014). doi:10.1038/nm.3594 Authors: Claudia Mauri & Kiran Nistala Regulatory B cells exert an immunosuppressive role by secreting the cytokine interleukin-10 (IL-10). Two studies have now identified B cell–derived IL-35 as both an inducer and a mediator ...

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Young blood rejuvenates old brains

05.06.2014 | Steven M Paul; Kiran Reddy, Nature Medicine, 2014

Nature Medicine 20, 582 (2014). doi:10.1038/nm.3597 Authors: Steven M Paul & Kiran Reddy Age-related cognitive decline occurs in many mammals, including humans, resulting from a decline in hippocampal function, and it is associated with reduced synaptic plasticity in ...

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Dengue virus: An enhanced model for dengue virus

05.06.2014 | Alison Farrell, Nature Medicine, 2014

Nature Medicine 20, 595 (2014). doi:10.1038/nm.3607 Author: Alison Farrell

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Stay the course

05.06.2014 | Nature Medicine, 2014

Nature Medicine 20, 561 (2014). doi:10.1038/nm.3608 Key stakeholders, journals and funders must enable the additional research and early data sharing needed to advance the adoptive T cell therapy field as a whole.

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