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1.619 Aktuelle Fachpublikationen in Journal of Natural Products

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Revised Stereochemistry of Ficifolidione and Its Biological Activities against Insects and Cells

12.12.2014 | Hisashi Nishiwaki; Satomi Fujiwara; Tuti Wukirsari; Hiroyuki Iwamoto; Shigeki Mori; Kosuke Nishi; Takuya Sugahara; S ..., Journal of Natural Products, 2014

Ficifolidione (1), a moderately active insecticidal compound from two species of Myrtaceae, and its derivatives were synthesized to evaluate their insecticidal activity. X-ray crystallographic analyses and specific rotation values of ficifolidione and its C-4 (2) demonstrated that the structure ...


Pentacyclic Antibiotics from a Tidal Mud Flat-Derived Actinomycete

11.12.2014 | Kyuho Moon; Beomkoo Chung; Yoonho Shin; Arnold L. Rheingold; Curtis E. Moore; Sung Jean Park; Sunghyouk Park; Sang K ..., Journal of Natural Products, 2014

The combination of investigating a unique source of chemically prolific bacterium with an LC/MS-based bacterial strain selection approach resulted in the discovery of two new secondary metabolites, buanmycin (1) and buanquinone (2), from the culture of a marine Streptomyces strain, which was ...


Isolation and Stereospecific Synthesis of Janolusimide B from a New Zealand Collection of the Bryozoan Bugula flabellata

10.12.2014 | Jiayi Wang; Michèle R. Prinsep; Dennis P. Gordon; Michael J. Page; Brent R. Copp, Journal of Natural Products, 2014

Journal of Natural Products DOI: 10.1021/np500752y


α-Hexylcinnamaldehyde Inhibits the Genotoxicity of Environmental Pollutants in the Bacterial Reverse Mutation Assay

10.12.2014 | Silvia Di Giacomo; Gabriela Mazzanti; Maria Grazia Sarpietro; Antonella Di Sotto, Journal of Natural Products, 2014

The antimutagenicity of α-hexylcinnamaldehyde (1), a semisynthetic and more stable derivative of cinnamaldehyde, was evaluated against common environmental pollutants in the bacterial reverse mutation assay. The pre-, co-, and post-treatment protocols were applied to assess the involvement of ...


Reniochalistatins A–E, Cyclic Peptides from the Marine Sponge Reniochalina stalagmitis

09.12.2014 | Kai-Xuan Zhan; Wei-Hua Jiao; Fan Yang; Jing Li; Shu-Ping Wang; Yu-Shan Li; Bing-Nan Han; Hou-Wen Lin, Journal of Natural Products, 2014

Five new cyclic peptides (including four heptapeptides and one octapeptide), reniochalistatins A–E (1–5), were isolated and characterized from the marine sponge Reniochalina stalagmitis collected off Yongxing Island in the South China Sea. Their structures were assigned on the basis of HRESIMS, ...


Antibacterial Ilicicolinic Acids C and D and Ilicicolinal from Neonectria discophora SNB-CN63 Isolated from a Termite Nest

05.12.2014 | Charlotte Nirma; Véronique Eparvier; Didier Stien, Journal of Natural Products, 2014

Journal of Natural Products DOI: 10.1021/np500080m


Evaluation of Lignans from Heliopsis helianthoides var. scabra for Their Potential Antimetastatic Effects in the Brain

05.12.2014 | Zsanett Hajdu; János Haskó; István A. Krizbai; Imola Wilhelm; Nikoletta Jedlinszki; Csilla Fazakas; Judit Molnár; Pe ..., Journal of Natural Products, 2014

Two new arylbenzofuran-type neolignans, 1″-dehydroegonol 3″-methyl ether (1) and egonol 3″-methyl ether (2), and four known lignan derivatives, namely, helioxanthin (3), (7E)-7,8-dehydroheliobuphthalmin (4), heliobuphthalmin (5), and 7-acetoxyhinokinin (6), were isolated from a chloroform-soluble ...


Endophytes Are Hidden Producers of Maytansine in Putterlickia Roots

05.12.2014 | Souvik Kusari; Marc Lamshöft; Parijat Kusari; Sebastian Gottfried; Sebastian Zühlke; Kathrin Louven; Ute Hentschel; ..., Journal of Natural Products, 2014

Several recent studies have lent evidence to the fact that certain so-called plant metabolites are actually biosynthesized by associated microorganisms. In this work, we show that the original source organism(s) responsible for the biosynthesis of the important anticancer and cytotoxic compound ...


Dietary Acetylenic Oxylipin Falcarinol Differentially Modulates GABAA Receptors

04.12.2014 | Marta Magdalena Czyzewska; Lukasz Chrobok; Alan Kania; Magdalena Jatczak; Federica Pollastro; Giovanni Appendino; Je ..., Journal of Natural Products, 2014

The dietary oxylipins falcarinol (1a) and falcarindiol (1b) trap thiols by direct nucleophilic addition to their diyne system, but despite this, only falcarinol (1a) is a reversible agonist of cannabinoid receptors, providing a rationale for comparing their activity also on other neuronal ...


Biosynthetic Origins of the Epoxyquinone Skeleton in Epoxyquinols A and B

03.12.2014 | Katsuki Fujita; Fumihiro Ishikawa; Hideaki Kakeya, Journal of Natural Products, 2014

The biosynthetic origins of epoxyquinols A (1) and B (2) produced by an unidentified fungus have attracted considerable interest because these compounds could be assembled from a biosynthetic precursor, epoxycyclohexenone aldehyde (3), via an electrocyclization/intermolecular Diels–Alder ...


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