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1.820 Aktuelle Fachpublikationen in Journal of Natural Products

mit folgenden Suchkriterien:

Discovery and Synthesis of Boletopsins 13 and 14, Brominated Fungal Metabolites of Terrestrial Origin

24.07.2015 | Andrew M. Beekman; Stewart W. Wossa; Oromo Kevo; Paul Ma; Russell A. Barrow, Journal of Natural Products, 2015

Journal of Natural Products DOI: 10.1021/acs.jnatprod.5b00202


Amantelides A and B, Polyhydroxylated Macrolides with Differential Broad-Spectrum Cytotoxicity from a Guamanian Marine Cyanobacterium

23.07.2015 | Lilibeth A. Salvador-Reyes; Jennifer Sneed; Valerie J. Paul; Hendrik Luesch, Journal of Natural Products, 2015

Cytotoxicity-guided fractionation of a Guamanian cyanobacterial collection yielded the new compounds amantelides A (1) and B (2). These polyketides are characterized by a 40-membered macrolactone ring consisting of a 1,3-diol and contiguous 1,5-diol units and a tert-butyl substituent. Amantelide ...


Characterization of l-Digitoxosyl-phenanthroviridin from Streptomyces venezuelae ISP5230

23.07.2015 | Andrew W. Robertson; Camilo F. Martinez-Farina; Raymond T. Syvitski; David L. Jakeman, Journal of Natural Products, 2015

Journal of Natural Products DOI: 10.1021/acs.jnatprod.5b00277


Triterpenoids with Promoting Effects on the Differentiation of PC12 Cells from the Steamed Roots of Panax notoginseng

22.07.2015 | Cheng-Zhen Gu; Jun-Jiang Lv; Xiao-Xia Zhang; Yi-Jun Qiao; Hui Yan; Yan Li; Dong Wang; Hong-Tao Zhu; Huai-Rong Luo; C ..., Journal of Natural Products, 2015

The roots of Panax notoginseng, an important Chinese medicinal plant, have been used traditionally in both the raw and processed forms, due to the different chemical constituents and bioactivities found. Thirty-eight dammarane-type triterpenoid saponins were isolated from the steam-processed ...


Bisabolane-Type Sesquiterpenoids from the Whole Plant of Parasenecio rubescens

22.07.2015 | An Jin; Wen-Ming Wu; Heng-Yi Yu; Ming Zhou; Ye Liu; Tian Tian; Han-Li Ruan, Journal of Natural Products, 2015

Twenty-two new highly oxygenated bisabolane-type sesquiterpenoids, pararubin A–V (1–22), were isolated from the whole plant of Parasenecio rubescens. The structure determination of 1–22, including the assignment of their relative configurations, was accomplished by extensive 1D and 2D NMR ...


Glucosinolate Diversity in Bretschneidera sinensis of Chinese Origin

21.07.2015 | Sabine Montaut; Wei-Dong Zhang; Jean-Marc Nuzillard; Gina R. De Nicola; Patrick Rollin, Journal of Natural Products, 2015

The glucosinolate (GL) profile in several plant parts (leaf, branch, bark, root, and fruit) of Bretschneidera sinensis from three geographical regions of the People’s Republic of China was established for the first time by HPLC. During this investigation, benzyl GL (1), 4-hydroxybenzyl GL (2), ...


Dereplicating and Spatial Mapping of Secondary Metabolites from Fungal Cultures in Situ

20.07.2015 | Vincent P. Sica; Huzefa A. Raja; Tamam El-Elimat; Vilmos Kertesz; Gary J. Van Berkel; Cedric J. Pearce; Nicholas H. ..., Journal of Natural Products, 2015

Ambient ionization mass spectrometry techniques have recently become prevalent in natural product research due to their ability to examine secondary metabolites in situ. These techniques retain invaluable spatial and temporal details that are lost through traditional extraction processes. ...


Vanillic Acid Inhibits Inflammatory Pain by Inhibiting Neutrophil Recruitment, Oxidative Stress, Cytokine Production, and NFκB Activation in Mice

20.07.2015 | Cássia Calixto-Campos; Thacyana T. Carvalho; Miriam S. N. Hohmann; Felipe A. Pinho-Ribeiro; Victor Fattori; Marília ..., Journal of Natural Products, 2015

Vanillic acid (1) is a flavoring agent found in edible plants and fruits. It is an oxidized form of vanillin. Phenolic compounds form a substantial part of plant foods used as antioxidants with beneficial biological activities. These compounds have received considerable attention because of their ...


Isolation and Structure Elucidation of Fujikurins A–D: Products of the PKS19 Gene Cluster in Fusarium fujikuroi

20.07.2015 | Katharina Walburga von Bargen; Eva-Maria Niehaus; Isabel Krug; Klaus Bergander; Ernst-Ulrich Würthwein; Bettina Tudz ..., Journal of Natural Products, 2015

Fusarium fujikuroi is a member of the Gibberella fujikuroi species complex and well known for the production of gibberellins and mycotoxins including fusarins and fusaric acid. A recent genome sequencing study revealed that the fungus has the genetic potential to produce many more secondary ...


Endophytic Diaporthe sp. LG23 Produces a Potent Antibacterial Tetracyclic Triterpenoid

17.07.2015 | Gang Li; Souvik Kusari; Parijat Kusari; Oliver Kayser; Michael Spiteller, Journal of Natural Products, 2015

A new lanostanoid, 19-nor-lanosta-5(10),6,8,24-tetraene-1α,3β,12β,22S-tetraol (1), characterized by the presence of an aromatic B ring and hydroxylated at C-1, C-3, C-12, and C-22, was isolated from an endophytic fungus, Diaporthe sp. LG23, inhabiting leaves of the Chinese medicinal plant Mahonia ...


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