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2.137 Aktuelle Fachpublikationen in Journal of Natural Products

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Structure of a Precursor to the Blue Components Produced in the Blue Discoloration in Japanese Radish (Raphanus sativus) Roots

29.04.2016 | Katsunori Teranishi; Nagata Masayasu, Journal of Natural Products, 2016

The internal blue discoloration in Japanese radish (Raphanus sativus L.) roots has been reported to be a physiological phenomenon after harvest and poses a significant problem for farmers. To avoid this discoloration, the fundamental development of new radish cultivars that do not undergo ...


Rebaudiosides R and S, Minor Diterpene Glycosides from the Leaves of Stevia rebaudiana

27.04.2016 | Mohamed A. Ibrahim; Douglas L. Rodenburg; Kamilla Alves; Wilmer H. Perera; Frank R. Fronczek; John Bowling; James D. ..., Journal of Natural Products, 2016

Two new diterpene glycosides have been isolated from a commercial extract of the leaves of Stevia rebaudiana. Compound 1 was shown to be 13-[(2-O-β-d-glucopyranosyl-3-O-β-d-glucopyranosyl-β-d-xylopyranosyl)oxy]ent-kaur-16-en-19-oic acid β-d-glucopyranosyl ester (rebaudioside R), while compound 2 ...


Nitric Oxide Inhibitory Meroterpenoids from the Fungus Penicillium purpurogenum MHZ 111

27.04.2016 | Jing Sun; Zhi-Xiang Zhu; Yue-Lin Song; Dan Dong; Jiao Zheng; Ting Liu; Yun-Fang Zhao; Daneel Ferreira; Jordan K. Zja ..., Journal of Natural Products, 2016

Five new meroterpenoids, purpurogenolides A–E (1–5), and four known metabolites (6–9) were isolated from the solid substrate fermentation cultures of the fungus Penicillium purpurogenum MHz 111. The structures of the new meroterpenoids were elucidated by analysis of spectroscopic and ...


Bioactive Dihydro-β-agarofuran Sesquiterpenoids from the Australian Rainforest Plant Maytenus bilocularis

27.04.2016 | Mario Wibowo; Claire Levrier; Martin C. Sadowski; Colleen C. Nelson; Qian Wang; Jeff Holst; Peter C. Healy; Andreas ..., Journal of Natural Products, 2016

Chemical investigations of the CH2Cl2 extract obtained from the leaves of the Australian rainforest tree Maytenus bilocularis afforded three new dihydro-β-agarofurans, bilocularins A–C (1–3), and six known congeners, namely, celastrine A (4), 1α,6β,8α-triacetoxy-9α-benzoyloxydihydro-β-agarofuran ...


(±)-Japonicols A–D, Acylphloroglucinol-Based Meroterpenoid Enantiomers with Anti-KSHV Activities from Hypericum japonicum

26.04.2016 | Linzhen Hu; Yongbo Xue; Jinwen Zhang; Hucheng Zhu; Chunmei Chen; Xiao-Nian Li; Junjun Liu; Zhenzhen Wang; Yu Zhang; ..., Journal of Natural Products, 2016

(±)-Japonicols A–D (1a/1b–4a/4b), four pairs of new phloroglucinol-based terpenoid enantiomers, were isolated from Hypericum japonicum. Their absolute configurations were confirmed through comparison of their experimental and calculated electronic circular dichroism spectra and single-crystal ...


Furofuran Lignan Glucosides with Estrogen-Inhibitory Properties from the Bangladeshi Medicinal Plant Terminalia citrina

25.04.2016 | Md. Abdul Muhit; Kaoru Umehara; Kanami Mori-Yasumoto; Hiroshi Noguchi, Journal of Natural Products, 2016

Extracts from the leaves of the Bangladeshi medicinal plant Terminalia citrina were prepared, and 13 new furofuran lignan glucosides, terminalosides A–K (1–4, 6–12), 2-epiterminaloside D (5), and 6-epiterminaloside K (13), were characterized using various spectroscopic techniques. Twelve of the ...


Pregnane-10,2-carbolactones from a Hawaiian Marine Sponge in the Genus Myrmekioderma

22.04.2016 | Jingqiu Dai; Wesley Y. Yoshida; Michelle Kelly; Philip Williams, Journal of Natural Products, 2016

Four new pregnanes, 3β,4β-dihydroxy-17-methyl-17α-pregna-5,13-diene-10,2-carbolactone (1), 6β-chloro-3β-hydroxy-17-methyl-17α-pregna-4,13-diene-10,2-carbolactone (2), 3β-hydroxy-6β-methoxy-17-methyl-17α-pregna-4,13-diene-10,2-carbolactone (3), and ...


Cigarette Smoke-Induced Lung Disease Predisposes to More Severe Infection with Nontypeable Haemophilus influenzae: Protective Effects of Andrographolide

22.04.2016 | W. S. Daniel Tan; Hong Yong Peh; Wupeng Liao; Chu Hui Pang; Tze Khee Chan; Suk Hiang Lau; Vincent T. Chow; W. S. Fre ..., Journal of Natural Products, 2016

Cigarette smoke (CS) is associated with many maladies, one of which is chronic obstructive pulmonary disease (COPD). As the disease progresses, patients are more prone to develop COPD exacerbation episodes by bacterial infection, particularly to nontypeable Haemophilus influenza (NTHi) infection. ...


Tadehaginosides A–J, Phenylpropanoid Glucosides from Tadehagi triquetrum, Enhance Glucose Uptake via the Upregulation of PPARγ and GLUT-4 in C2C12 Myotubes

21.04.2016 | Xiaopo Zhang; Changyu Chen; Yonghui Li; Deli Chen; Lin Dong; Wei Na; Chongming Wu; Junqing Zhang; Youbin Li, Journal of Natural Products, 2016

Ten new phenylpropanoid glucosides, tadehaginosides A–J (1–10), and the known compound tadehaginoside (11) were obtained from Tadehagi triquetrum. These phenylpropanoid glucosides were structurally characterized through extensive physical and chemical analyses. Compounds 1 and 2 represent the ...


Efficient Synthesis of Glaziovianin A Isoflavone Series from Dill and Parsley Extracts and Their in Vitro/in Vivo Antimitotic Activity

21.04.2016 | Victor V. Semenov; Dmitry V. Tsyganov; Marina N. Semenova; Roman N. Chuprov-Netochin; Mikhail M. Raihstat; Leonid D. ..., Journal of Natural Products, 2016

A concise six-step protocol for the synthesis of isoflavone glaziovianin A (GVA) and its alkoxyphenyl derivatives 9 starting with readily available plant metabolites from dill and parsley seeds was developed. The reaction sequence involved an efficient conversion of the key intermediate epoxides ...


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