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1.660 Aktuelle Fachpublikationen in Journal of Natural Productsrss
20.02.2015 | Christine M. Theodore; Nicholas Lorig-Roach; Patrick C. Still; Tyler A. Johnson; Marija Drašković; Joshua A. Schwoch ..., Journal of Natural Products, 2015
Sampling of California nearshore sediments resulted in the isolation of a Gram-negative bacterium, Photobacterium halotolerans, capable of producing unusual biosynthetic products. Liquid culture in artificial seawater-based media provided cyclic depsipeptides including four known compounds, ...
20.02.2015 | Anna Andolfi; Angela Boari; Marco Evidente; Alessio Cimmino; Maurizio Vurro; Gavin Ash; Antonio Evidente, Journal of Natural Products, 2015
A virulent strain of Diaporthe gulyae, isolated from stem cankers of sunflower and known to be pathogenic to saffron thistle, has been shown to produce both known and previously undescribed metabolites when grown in either static liquid culture or a bioreactor. Together with phomentrioloxin, a ...
20.02.2015 | Meri Emili F. Pinto; João M. Batista, Jr.; Johannes Koehbach; Pratibha Gaur; Abhinay Sharma; Myna Nakabashi; Eduardo ..., Journal of Natural Products, 2015
Journal of Natural Products DOI: 10.1021/np5007668
20.02.2015 | Seong-Hwan Kim; Yoonho Shin; So-Hyoung Lee; Ki-Bong Oh; Sang Kook Lee; Jongheon Shin; Dong-Chan Oh, Journal of Natural Products, 2015
Salternamides A–D (1–4), the first secondary metabolites discovered from saltern-derived actinomycetes, were isolated from a halophilic Streptomyces strain isolated from a saltern on Shinui Island in the Republic of Korea. The planar structures of the salternamides, which are new members of the ...
20.02.2015 | Kazufumi Toume; Tadashi Habu; Midori A. Arai; Takashi Koyano; Thaworn Kowithayakorn; Masami Ishibashi, Journal of Natural Products, 2015
Journal of Natural Products DOI: 10.1021/acs.jnatprod.5b00061
19.02.2015 | Sudharshan Madapa; Wayne W. Harding, Journal of Natural Products, 2015
N-Methyllaurotetanine (1) has been reported to display good affinity for the 5-HT1A receptor, but no structure–affinity studies have been performed to date. The commercially available alkaloid boldine (2) was used as the starting material for synthesis of various C-9 alkoxy analogues of ...
19.02.2015 | Oliver Callies; María P. Sánchez-Cañete; Francisco Gamarro; Ignacio A. Jiménez; Santiago Castanys; Isabel L. Bazzocchi, Journal of Natural Products, 2015
Multidrug resistance (MDR) caused by the overexpression of ABC drug transporters is a major obstacle in clinical cancer chemotherapy and underlines the urgent need for the development of new, potent, and safe reversal agents. Toward this goal, reported herein are the structure elucidation and ...
18.02.2015 | Wei-Yu Chen; Fang-Yu Chen; An-Sheng Lee; Kuan-Hsiang Ting; Chia-Ming Chang; Jing-Fang Hsu; Wei-Shine Lee; Joen-Rong ..., Journal of Natural Products, 2015
Highly electronegative low-density lipoprotein (LDL) L5 induces endothelial cell (EC) apoptosis, which leads to the development of atherosclerosis. We examined the effects of sesamol (1), a natural organic component of sesame oil, on plasma L5 levels and atherosclerosis development in a rodent ...
17.02.2015 | George R. Pettit; Pablo M. Arce; Jean-Charles Chapuis; Christian B. Macdonald, Journal of Natural Products, 2015
The recent advances in the development of antibody and other drug conjugates for targeted cancer treatment have further increased the need for powerful cancer cell growth inhibitors. Toward that objective we have extended our earlier discovery of the remarkable anticancer bacillistatins 1 and 2 ...
17.02.2015 | Thanh-Huong Bui; Victor Wray; Manfred Nimtz; Torgils Fossen; Michael Preisitsch; Gudrun Schröder; Kristian Wende; St ..., Journal of Natural Products, 2015
Journal of Natural Products DOI: 10.1021/acs.jnatprod.5b00138