01.04.2011 | Neibecker, Markus; Schwarze‐Zander, Carolynne; Rockstroh, Jürgen K.; Spengler, Ulrich; Blackard, Jason T., Journal of Medical Virology, 2011

Abstract Multiple genotypes of GB virus C (GBV‐C)—a non‐pathogenic flavivirus—have been identified to date, although they are not uniformly distributed worldwide. It has also been suggested that GBV‐C genotype may play a role in modulating HIV disease; however, the prevalence and genotype ...

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01.04.2011 | Al‐Buhtori, Marwan; Moore, Lynette; Benbow, Emyr W.; Cooper, Robert J., Journal of Medical Virology, 2011

Abstract This study was undertaken to investigate the occurrence of viral infection in fetal death by examining tissues for the presence of DNA of several viral agents. Tissue specimens including heart, kidney, liver, lung, and placenta of 73 cases of fetal death were examined with 27 ...

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01.04.2011 | Skog, Oskar; Korsgren, Olle; Frisk, Gun, Journal of Medical Virology, 2011

Abstract Present knowledge of innate immunity in infected cells relies on studies of cell lines and animal models. In this study, primary human pancreatic islets of Langerhans were used to study virus–host interactions in a model of the possible induction of type 1 diabetes by enterovirus ...

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01.04.2011 | KrennHrubec, Keris; Mrad, Karima; Sriha, Badreddine; Ayed, Farhat Ben; Bottalico, Danielle M.; Ostolaza, Janae; Smit ..., Journal of Medical Virology, 2011

Abstract Cervical cancer is the second most common cancer among Tunisian women, and the incidence rates vary by region. Three Tunisian registries report age‐standardized rates of 6.3/105 in the central region, 5.4/105 in the north, and 2.7/105 in the south. High‐risk human papillomavirus ...

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01.04.2011 | Chao, Yan; Jing, Yongzheng; Jia, Yuping; Wang, Yun; Zhao, Chengquan; Luo, Bing, Journal of Medical Virology, 2011

Abstract The Epstein–Barr virus (EBV) BamHI‐C fragment rightward reading frame 1 (BCRF1)‐coded viral interleukin‐10 (vIL‐10), exhibits high homology with human interleukin‐10 (hIL‐10) gene. The protein product vIL‐10, which shares some functional properties with hIL‐10, primarily mediates ...

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01.04.2011 | Carcopino, Xavier; Bolger, Noel; Henry, Mireille; Mancini, Julien; Boubli, Léon; Olive, Daniel; Cleary, Sinea ..., Journal of Medical Virology, 2011

Abstract The persistence of high‐risk HPV (HR‐HPV) infection is necessary for the development of cervical intraepithelial neoplasia. The aim of this study was to evaluate if HR‐HPV typing and HPV16, 18, 31, and 33 quantitation are predictive for type‐specific infection persistence and/or ...

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01.04.2011 | Chatterjee, Koushik; Williamson, Anna‐Lise; Hoffman, Margaret; Dandara, Collet, Journal of Medical Virology, 2011

Abstract Only a small fraction of women infected with human papillomavirus (HPV) progress to cervical cancer pointing to additional risk factors including host genetics that might play a role in development of cervical cancer. Caspase‐8 (encoded by CASP8 gene) is crucial in generating cell ...

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01.04.2011 | He, Yi; Zhang, Jie; Zhong, Li; Chen, Xue; Liu, Hu‐Min; Wan, Li‐Ke; Wang, Huan; Li, Hong; Tian, Li; Hu, ..., Journal of Medical Virology, 2011

Abstract The objectives of the study were to estimate the prevalence of anti‐hepatitis C virus (HCV) positivity among blood donors from Chengdu, China, and to determine risk factors associated with infection. In this study, data were collected from volunteer blood donors between July 2006 ...

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01.04.2011 | Calado, Rita Almeida; Rocha, Maria Raquel; Parreira, Ricardo; Piedade, João; Venenno, Teresa; Esteves, Aida, Journal of Medical Virology, 2011

Abstract Hepatitis C virus (HCV) infects 2–3% of the world population and intravenous drug consumption is the leading cause of transmission in industrialized countries. The unavailability of data on the molecular epidemiology of HCV infection in Portugal prompted the study of HCV subtypes ...

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01.04.2011 | Cheng, Pin‐Nan; Liu, Wen‐Chun; Tsai, Hung‐Wen; Wu, I‐Chin; Chang, Ting‐Tsung; You ..., Journal of Medical Virology, 2011

Abstract Covalently closed circular DNA (cccDNA) of hepatitis B virus (HBV) is difficult to eradicate using current antiviral therapy. This study compares cccDNA reduction with relation to liver histology in nucleoside/nucleotide‐naïve chronic hepatitis B patients receiving oral antiviral ...

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