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1.488 Aktuelle Fachpublikationen in Biomacromolecules

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Thin Film of Lignocellulosic Nanofibrils with Different Chemical Composition for QCM-D Study

14.06.2013 | Akio Kumagai; Seung-Hwan Lee; Takashi Endo, Biomacromolecules, 2013

Thin films of lignocellulosic nanofibrils (LCNFs) with different chemical compositions were prepared for real-time observation of their enzymatic adsorption and degradation behavior by using a quartz crystal microbalance with dissipation monitoring (QCM-D). LCNFs were obtained by disk milling ...

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Carboxymethyl-Chitosan-Tethered Lipid Vesicles: Hybrid Nanoblanket for Oral Delivery of Paclitaxel

14.06.2013 | Nitin Joshi; Rama Saha; Thanigaivel Shanmugam; Biji Balakrishnan; Prachi More; Rinti Banerjee, Biomacromolecules, 2013

We describe the development and evaluation of a hybrid lipopolymeric system comprising carboxymethyl chitosan (CMC), covalently tethered to phosphatidylethanolamine units on the surface of lipid nanovesicles, for oral delivery of paclitaxel. The bioploymer is intended to act as a blanket, ...

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Encapsulation of Enzymes in Layer-by-Layer (LbL) Structures: Latest Advances and Applications

13.06.2013 | Omar. S. Sakr; Gerrit Borchard, Biomacromolecules, 2013

Layer-by-Layer (LbL) technology has become an active area of research and is currently considered a hot topic with many potential applications, especially in the pharmaceutical and biopharmaceutical fields. This review is providing an overview of current approaches and applications of LbL ...

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Modeling Progression of Fluorescent Probes in Bioinspired Lignocellulosic Assemblies

12.06.2013 | Gabriel Paës; Sally Burr; Marie-Belle Saab; Michaël Molinari; Véronique Aguié-Béghin; Brigitte Chabbert, Biomacromolecules, 2013

Progression of enzymes in lignocellulosic biomass is a crucial parameter in biorefinery processes, and it appears to be one of the limiting factors in optimizing lignocellulose degradation. In order to assay the importance of the chemical and structural features of the substrate matrix on ...

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Preparation and Characterization of Kraft Lignin-Based Moisture-Responsive Films with Reversible Shape-Change Capability

10.06.2013 | Ian Dallmeyer; Sudip Chowdhury; John F. Kadla, Biomacromolecules, 2013

Preparation of moisture-responsive Kraft lignin-based materials by electrospinning blends of Kraft lignin fractions with different physical properties is presented. The differences in thermal mobility between lignin fractions are shown to influence the degree of interfiber fusion occurring ...

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Dispersible and Thermal Stable Nanofibrils Derived from Glycated Whey Protein

10.06.2013 | Gang Liu; Qixin Zhong, Biomacromolecules, 2013

Formation of nanofibrils by heating proteins at pH 2.0 has been studied extensively because of the potential as novel biomaterials. However, nanofibrils of whey proteins have poor dispersibility and heat stability, limiting their application in fluidic and transparent products. We report, for ...

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Molecular Size Characterization and Kinetics Studies on Hydrolysis of Pullulan by Pullulanase in an Entangled Alginate Medium

07.06.2013 | Ghina Ali; Christophe Rihouey; Véronique Larreta-Garde; Didier Le Cerf; Luc Picton, Biomacromolecules, 2013

The behavior of a hydrolytic enzyme (pullulanase) toward its substrate (pullulan) in the presence of a nonsubstrate (alginate), both below and above the critical entanglement concentration (C*), was studied. The hydrolysis kinetics were studied with the enzyme and alginate concentrations ...

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Reconfigurable Biodegradable Shape-Memory Elastomers via Diels–Alder Coupling

07.06.2013 | Chi Ninh; Christopher J Bettinger, Biomacromolecules, 2013

Synthetic biodegradable elastomers are a class of polymers that have demonstrated far-reaching utility as biomaterials for use in many medical applications. Biodegradable elastomers can be broadly classified into networks prepared by either step-growth or chain-growth polymerization. Each ...

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Multifunctional Nanoparticles Improve Therapeutic Effect for Breast Cancer by Simultaneously Antagonizing Multiple Mechanisms of Multidrug Resistance

07.06.2013 | Qi Yin; Jianan Shen; Zhiwen Zhang; Haijun Yu; Lingli Chen; Wangwen Gu; Yaping Li, Biomacromolecules, 2013

For efficient reversal of multidrug resistance (MDR) in chemotherapy for breast cancer, multifunctional self-assembled nanoparticles (MSN) based on a new amphiphilic copolymer consisting of bioreducible poly[bis(2-hydroxylethyl)-disulfide-diacrylate-β-tetraethylenepentamine] and ...

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Mild and Efficient Strategy for Site-Selective Aldehyde Modification of Glycosaminoglycans: Tailoring Hydrogels with Tunable Release of Growth Factor

07.06.2013 | Shujiang Wang; Oommen P. Oommen; Hongji Yan; Oommen P. Varghese, Biomacromolecules, 2013

Aldehydes have been used as an important bioorthogonal chemical reporter for conjugation of large polymers and bioactive substances. However, generating aldehyde functionality on carbohydrate-based biopolymers without changing its native chemical structure has always persisted as a ...

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