12.05.2013 | BRETT J. CARROLL, FERNANDO M. CONTRERAS‐VALDES, E. KEVIN HEIST, CONOR D. BARRETT, STEPHAN B. DANIK, JEREMY N. RUSKIN ..., Journal of Cardiovascular Electrophysiology, 2013

Abstract Background Radiofrequency (RF) ablation in the posterior left atrium has risk of thermal injury to the adjacent esophagus. Increased intraluminal esophageal temperature has been correlated with risk of esophageal injury. The objective of this study was to compare esophageal ...

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12.05.2013 | ANDREA DI CORI, GIULIO ZUCCHELLI, SIMONE ROMANO, MARIA GRAZIA BONGIORNI, Journal of Cardiovascular Electrophysiology, 2013

Abstract A 34‐year‐old woman with a congenital long‐QT syndrome LQTS type 2, implanted 10 years before with a single chamber implantable defibrillator (ICD) for secondary prevention, was admitted to our hospital to remove the malfunctioning ventricular ICD lead (Endotak Reliance S 0128, ...

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12.05.2013 | Jennifer L. Gori, Brian C. Beard, Nathaniel P. Williams, Christina Ironside, Debra Swanson, R. Scott McIvor, H. P. Kiem, The Journal of Gene Medicine, 2013

ABSTRACT Background Nonmyeloablative allogeneic hematopoietic stem cell (HSC) transplantation can cure malignant and nonmalignant diseases affecting the hematopoietic system, such as severe combined immunodeficiencies, aplastic anemia and hemoglobinopathies. Although nonmyeloablative is ...

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11.05.2013 | Paul Kay, Yit C. Yang, Luminita Paraoan, Journal of Cellular and Molecular Medicine, 2013

Abstract The structural and functional integrity of the retinal pigment epithelium (RPE) is fundamental for maintaining the function of the neuroretina. These specialized cells form a polarized monolayer that acts as the retinal–blood barrier, separating two distinct environments with ...

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11.05.2013 | Liang Zhao, Patricia J. Tyler, John Starnes, Christy L. Bratcher, Darrell Rankins, Thomas A. McCaskey, Luxin Wang, Journal of Applied Microbiology, 2013

Abstract Aims The objectives of this study were to investigate the correlations between Shiga toxin producing Escherichia coli (STEC) shedding and fecal microflora in beef cattle and to identify functional species that might be used for STEC control. Methods and Results Fecal ...

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11.05.2013 | Akhilesh S. Dhanani, Tamishraha Bagchi, Journal of Applied Microbiology, 2013

Abstract Aims To analyse the expression of EF‐Tu in Lactobacillus strains with response to mucin exposure and its role in interfering with adhesion of enteropathogens to mucin. Methods and Results The Lactobacillus strains were analysed for their ability to adhere to immobilized ...

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11.05.2013 | Yuefang Gao, Han Liu, Chuanjing An, Yuhong Shi, Xia Liu, Wanqiong Yuan, Bing Zhang, Jin Yang, Caixia Yu, Hongbo Gao, The Plant Journal, 2013

Summary ARC5 is a dynamin‐related GTPase essential for the division of chloroplasts in plants. The arc5 mutant frequently exhibits enlarged, dumbbell‐shaped chloroplasts, indicating a role for ARC5 in the constriction of the chloroplast division site. In a screen for chloroplast division ...

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11.05.2013 | S.A Okorochenkov, G.A. Zheltukhina, E.P. Mirchink, E.B. Isakova, A.V. Feofanov, V.E. Nebolsin, Chemical Biology & Drug Design, 2013

Abstract The increasing prevalence of antibiotic‐resistant bacterial strains has necessitated the synthesis of novel antibacterial agents. It was previously shown that naturally occurring metalloporphyrin hemin possesses dark antibacterial activity against Gram‐positive bacteria. To ...

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11.05.2013 | Peng Du, Lili Xu, Jiye Huang, Kunqian Yu, Rui Zhao, Bo Gao, Hualiang Jiang, Weili Zhao, Xuechu Zhen, Wei Fu, Chemical Biology & Drug Design, 2013

A series of indolebutylamine (IBA) derivatives were designed, synthesized and evaluated as a novel class of selective ligands for the dopamine 3 receptor (D3R). The most potent compound 11q binds to D3R with a Ki value of 124 nM and displays excellent selectivity over the dopamine 1 ...

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11.05.2013 | Carolina Mascayano, Victoria Espinosa, Silvia Sepúlveda‐Boza, Eric K. Hoobler, Steve Perry, Chemical Biology & Drug Design, 2013

Abstract In this study, we have investigated sixteen isoflavone and isoflavan derivatives as potential inhibitors of human lipoxygenases (platelet 12‐LOX, reticulocyte 15‐LOX‐1, and epithelial 15‐LOX‐2). The flavonoid baicalein, a known lipoxygenase inhibitor, was used as positive ...

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