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22.596 Aktuelle Fachpublikationen von Proceedings of the National Academy of Sciences

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Nanofluid of graphene-based amphiphilic Janus nanosheets for tertiary or enhanced oil recovery: High performance at low concentration [Applied Physical Sciences]

12.07.2016 | Dan Luo; Feng Wang; Jingyi Zhu; Feng Cao; Yuan Liu; Xiaogang Li; Richard C. Willson; Zhaozhong Yang; Ching-Wu Chu; Z ..., Proceedings of the National Academy of Sciences current issue, 2016

The current simple nanofluid flooding method for tertiary or enhanced oil recovery is inefficient, especially when used with low nanoparticle concentration. We have designed and produced a nanofluid of graphene-based amphiphilic nanosheets that is very effective at low concentration. Our ...

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Enzyme surface rigidity tunes the temperature dependence of catalytic rates [Biophysics and Computational Biology]

12.07.2016 | Geir Villy Isaksen; Johan Åqvist; Bjørn Olav Brandsdal, Proceedings of the National Academy of Sciences current issue, 2016

The structural origin of enzyme adaptation to low temperature, allowing efficient catalysis of chemical reactions even near the freezing point of water, remains a fundamental puzzle in biocatalysis. A remarkable universal fingerprint shared by all cold-active enzymes is a reduction of the ...

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Modular elements of the TPR domain in the Mps1 N terminus differentially target Mps1 to the centrosome and kinetochore [Cell Biology]

12.07.2016 | Joseph R. Marquardt; Jennifer L. Perkins; Kyle J. Beuoy; Harold A. Fisk, Proceedings of the National Academy of Sciences current issue, 2016

Faithful segregation of chromosomes to two daughter cells is regulated by the formation of a bipolar mitotic spindle and the spindle assembly checkpoint, ensuring proper spindle function. Here we show that the proper localization of the kinase Mps1 (monopolar spindle 1) is critical to both these ...

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Large-scale climatic and geophysical controls on the leaf economics spectrum [Ecology]

12.07.2016 | Gregory P. Asner; David E. Knapp; Christopher B. Anderson; Roberta E. Martin; Nicholas Vaughn, Proceedings of the National Academy of Sciences current issue, 2016

Leaf economics spectrum (LES) theory suggests a universal trade-off between resource acquisition and storage strategies in plants, expressed in relationships between foliar nitrogen (N) and phosphorus (P), leaf mass per area (LMA), and photosynthesis. However, how environmental conditions mediate ...

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Genetic evidence for natural selection in humans in the contemporary United States [Evolution]

12.07.2016 | Jonathan P. Beauchamp, Proceedings of the National Academy of Sciences current issue, 2016

Recent findings from molecular genetics now make it possible to test directly for natural selection by analyzing whether genetic variants associated with various phenotypes have been under selection. I leverage these findings to construct polygenic scores that use individuals’ genotypes to ...

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Correction for Landhuis, Science and Culture: Putting a game face on biomedical research [Correction]

12.07.2016 | Proceedings of the National Academy of Sciences current issue, 2016

SCIENCE AND CULTURE Correction for “Science and Culture: Putting a game face on biomedical research,” by Esther Landhuis, which appeared in issue 24, June 14, 2016, of Proc Natl Acad Sci USA (113:6577–6578; 10.1073/pnas.1607585113). The editors note that on page 6577, left column, first ...

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Direct calorimetric verification of thermodynamic instability of lead halide hybrid perovskites [Chemistry]

12.07.2016 | G. P. Nagabhushana; Radha Shivaramaiah; Alexandra Navrotsky, Proceedings of the National Academy of Sciences current issue, 2016

Hybrid perovskites, especially methylammonium lead iodide (MAPbI3), exhibit excellent solar power conversion efficiencies. However, their application is plagued by poor chemical and structural stability. Using direct calorimetric measurement of heats of formation, MAPbI3 is shown to be ...

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Tautomerization-dependent recognition and excision of oxidation damage in base-excision DNA repair [Biochemistry]

12.07.2016 | Chenxu Zhu; Lining Lu; Jun Zhang; Zongwei Yue; Jinghui Song; Shuai Zong; Menghao Liu; Olivia Stovicek; Yi Qin Gao; C ..., Proceedings of the National Academy of Sciences current issue, 2016

NEIL1 (Nei-like 1) is a DNA repair glycosylase guarding the mammalian genome against oxidized DNA bases. As the first enzymes in the base-excision repair pathway, glycosylases must recognize the cognate substrates and catalyze their excision. Here we present crystal structures of human NEIL1 ...

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Correction for Chappell and Rausher, Evolution of host range in Coleosporium ipomoeae, a plant pathogen with multiple hosts [Correction]

12.07.2016 | Proceedings of the National Academy of Sciences current issue, 2016

EVOLUTION Correction for “Evolution of host range in Coleosporium ipomoeae, a plant pathogen with multiple hosts,” by Thomas M. Chappell and Mark D. Rausher, which appeared in issue 19, May 10, 2016, of Proc Natl Acad Sci USA (113:5346–5351; first published April 25, 2016; ...

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Chromosome-level assembly of Arabidopsis thaliana Ler reveals the extent of translocation and inversion polymorphisms [Genetics]

12.07.2016 | Luis Zapata; Jia Ding; Eva-Maria Willing; Benjamin Hartwig; Daniela Bezdan; Wen-Biao Jiao; Vipul Patel; Geo Velikkak ..., Proceedings of the National Academy of Sciences current issue, 2016

Resequencing or reference-based assemblies reveal large parts of the small-scale sequence variation. However, they typically fail to separate such local variation into colinear and rearranged variation, because they usually do not recover the complement of large-scale rearrangements, including ...

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