01.10.2011 | Hitomi Soumiya; Hidefumi Fukumitsu; Shoei Furukawa, Journal of Neuroscience Research, 2011

Abstract Maternal infection during pregnancy is an environmental risk factor for the development of severe brain disorders in offspring, including schizophrenia and autism. However, little is known about the neurodevelopmental mechanisms underlying the association between prenatal exposure ...

mehr

01.10.2011 | Kathrine R. Weeks; Donard S. Dwyer; Eric J. Aamodt, Journal of Neuroscience Research, 2011

Abstract Numerous studies have implicated low levels of signaling in the Akt network with psychotic illnesses, and a growing body of literature has shown that all classes of antipsychotic drugs increase Akt signaling. The most clinically effective antipsychotic drug is clozapine. With ...

mehr

01.10.2011 | Shin Kato; Mineyoshi Aoyama; Hiroki Kakita; Hideki Hida; Ineko Kato; Tetsuya Ito; Tatenobu Goto; Mohamed H. Hussein; ..., Journal of Neuroscience Research, 2011

Abstract The hypoxia‐responsive cytokine erythropoietin (EPO) provides neuroprotective effects in the damaged brain during ischemic events and neurodegenerative diseases. The purpose of the present study is to evaluate the EPO/EPO receptor (EPOR) endogenous system between astrocyte and ...

mehr

01.10.2011 | Natalie R.S. Goldberg; Tom Hampton; Scott McCue; Ajit Kale; Charles K. Meshul, Journal of Neuroscience Research, 2011

Abstract Current behavioral measurements for motor impairment are not consistently sensitive in rodent models of partial nigrostriatal dopamine (DA) depletion. In addition to exploratory and somatosensory behavior, motor skills that are thought to be directly translatable to human ...

mehr

01.10.2011 | Sandra Werner; Klaus Unsicker; Oliver von Bohlen und Halbach, Journal of Neuroscience Research, 2011

Abstract Neurogenesis within the adult brain is restricted to selected areas, one of which is the dentate gyrus (DG). Several growth factors have been reported to affect neurogenesis in the adult DG. However, a role of fibroblast growth factor‐2 (FGF‐2) in adult hippocampal neurogenesis ...

mehr

01.10.2011 | Anna Papa; Dimitra Karabaxoglou; Athina Kansouzidou, Journal of Medical Virology, 2011

Abstract Cross‐reactions in serology are common among flaviviruses. During the outbreak of West Nile virus (WNV) infections in Greece in 2010, WNV IgM‐positive serum and cerebrospinal fluid samples were tested for the presence of IgM and IgG antibodies against Dengue virus (DENV) and ...

mehr

01.10.2011 | Anna Papa; Kostas Danis; Afroditi Athanasiadou; Maria Delianidou; Takis Panagiotopoulos, Journal of Medical Virology, 2011

Abstract A major outbreak of West Nile virus (WNV) lineage 2 infections was observed in 2010 in Greece. In order to check the persistence of WNV IgM antibodies, a second serum sample taken 75–180 days after onset of the illness from 29 patients with WNV infection was tested. A third sample ...

mehr

01.10.2011 | Mohamed Abugalia; Luis Cuevas; Andrew Kirby; Winifred Dove; Osamu Nakagomi; Toyoko Nakagomi; Majdi Kara; Rabia Gwede ..., Journal of Medical Virology, 2011

Abstract Rotaviruses and noroviruses are leading viral causes of diarrhoea in children. A cross‐sectional study was undertaken among children aged

mehr

01.10.2011 | Vasiliki Pogka; Athanasios Kossivakis; Antonios Kalliaropoulos; Afroditi Moutousi; Dionyssios Sgouras; Takis Panagio ..., Journal of Medical Virology, 2011

Abstract Viruses are the major cause of pediatric respiratory tract infection and yet many suspected cases of illness remain uncharacterized. This study aimed to determine the distribution of several respiratory viruses in children diagnosed as having influenza‐like illness, over the ...

mehr

01.10.2011 | T.L. Kresfelder; R. Janssen; L. Bont; M. Venter, Journal of Medical Virology, 2011

Abstract Respiratory syncytial virus is a leading cause of lower respiratory tract infection in infants. Disease severity has been linked to host immune responses and polymorphisms in genes associated with innate immunity. A large‐scale genetics study of single nucleotide polymorphisms ...

mehr