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2.559 Aktuelle Fachpublikationen von Future Medicine

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Ozenoxacin 1% cream in the treatment of impetigo: a multicenter, randomized, placebo- and retapamulin-controlled clinical trial

23.10.2014 | Savion Gropper; Nuria Albareda; Klaus Chelius; Dawie Kruger; Ismail Mitha; Yacoob Vahed; Mashra Gani; Fernando Garcí ..., Future Microbiology, 2014

ABSTRACT  Aim: We compared the efficacy and safety of ozenoxacin (a new nonfluorinated quinolone) 1% cream with placebo in the treatment of impetigo. Patients & methods: In a randomized, double-blind, multicenter study, patients received ozenoxacin cream or placebo cream twice daily for 5 days (a ...

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Genetic variation in platinating agent and taxane pathway genes as predictors of outcome and toxicity in advanced non-small-cell lung cancer

23.10.2014 | Jatinder Kaur Lamba; Brooke L Fridley; Taraswi M Ghosh; Qing Yu; Gaurav Mehta; Pankaj Gupta, Pharmacogenomics, 2014

Aim: Lung carcinoma is the most common malignancy and the leading cause of cancer deaths worldwide. Although clinical factors including age, performance status and stage influence the likelihood of benefit from and tolerability of chemotherapy, the genetic profile of individual patients may be an ...

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Risk factors for suicide in epilepsy patients

22.10.2014 | Hrvoje Hećimović; Zvonimir Popović, Future Neurology, 2014

ABSTRACT:  Suicidal behavior is not uncommon in epilepsy patients. Risk factors for suicidal ideation are associated with social and vocational disturbances, such as low economic status, lack of social support and unemployment and psychiatric comorbidity. In epilepsy patients, interictal ...

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Evolution of MRI of brain injury in concussion patients

22.10.2014 | Saeed Fakhran; Joseph Delic; Lea Alhilali, Future Neurology, 2014

Future Neurology September 2014, Vol. 9, No. 5, Pages 517-520.

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Use of electroconvulsive therapy in the treatment of catatonia

22.10.2014 | Daniel Gih; Neera Ghaziuddin, Future Neurology, 2014

ABSTRACT:  While the mechanisms of catatonia remain poorly understood, there are known and effective treatments for it, namely high-dose benzodiazepines and electroconvulsive therapy (ECT). For more than 75 years, ECT has been successfully used for the treatment of severe psychiatric disorders, ...

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Targeting retinoblastoma protein offers therapeutic opportunities for peripheral nerve injury

22.10.2014 | Anand Krishnan; Douglas W Zochodne, Future Neurology, 2014

Future Neurology September 2014, Vol. 9, No. 5, Pages 513-515.

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Peripheral progranulin levels do not reflect brain progranulin levels

22.10.2014 | Louis De Muynck; Philip Van Damme, Future Neurology, 2014

EVALUATION OF:  Nicholson AM, Finch NA, Thomas CS et al. Progranulin protein levels are differently regulated in plasma and CSF. Neurology 82(21), 1871–1878 (2014). Nicholson et al. report the first population-based comparative study of progranulin (GRN) levels in plasma and cerebrospinal fluid ...

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Animal models of stroke: translational potential at present and in 2050

22.10.2014 | Paco S Herson; Richard J Traystman, Future Neurology, 2014

ABSTRACT:  Translation from basic science bench research in ischemic stroke to bedside treatment of patients suffering ischemic stroke remains a difficult challenge. Despite literally hundreds of compounds and interventions that provide benefit in experimental models of cerebral ischemia, ...

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Cerebrospinal fluid α-synuclein in the differential diagnosis of parkinsonian syndromes

22.10.2014 | Niels HH Heegaard; Julia T Tanassi; Sara Bech; Lisette Salvesen; Peter Lüttge Jensen; Liliana CP Montezinho; Kristia ..., Future Neurology, 2014

ABSTRACT:  Aim: To evaluate the diagnostic value of the level of α-synuclein, DJ-1, and Alzheimer's disease markers in the cerebrospinal fluid (CSF) in patients with parkinsonian syndromes. Materials & methods: We measured α-synuclein, DJ-1 and Alzheimer's disease markers by quantitative ...

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Inflammatory cytokines kinetics define the severity and phase of nephropathia epidemica

14.10.2014 | Asia A Baigildina; Svetlana F Khaiboullina; Ekaterina V Martynova; Vladimir A Anokhin; Vincent C Lombardi; Albert A ..., Biomarkers in Medicine, 2014

Aims: Nephropathia epidemica (NE) is a form of hemorrhagic fever with renal syndrome associated with the Puumala virus species of Hantavirus. The pathogenesis of NE is not well understood; therefore, investigating the inflammatory cytokine response to infection may provide useful knowledge in ...

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