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2.635 Aktuelle Fachpublikationen von Future Medicine

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A possible future for the pharmaceutical industry

01.12.2014 | Peter Tolias, Personalized Medicine, 2014

Personalized Medicine November 2014, Vol. 11, No. 8, Pages 723-725.

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Cav3 T-type channels as drug targets for treating epilepsy

01.12.2014 | Wendy Guan; Robert F Stephens; J David Spafford, Future Neurology, 2014

Future Neurology November 2014, Vol. 9, No. 6, Pages 563-566.

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Facial neuropathy with imaging enhancement of the facial nerve: a case report

01.12.2014 | Sehreen Mumtaz; Matthew B Jensen, Future Neurology, 2014

ABSTRACT  A young women developed unilateral facial neuropathy 2 weeks after a motor vehicle collision involving fractures of the skull and mandible. MRI showed contrast enhancement of the facial nerve. We review the literature describing facial neuropathy after trauma and facial nerve ...

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A prospective study on bacterial and atypical etiology of acute exacerbation in chronic obstructive pulmonary disease

01.12.2014 | Alexandra Nakou; Joseph Papaparaskevas; Filia Diamantea; Nikoletta Skarmoutsou; Vlasis Polychronopoulos; Athanassios ..., Future Microbiology, 2014

ABSTRACT  Aim: The bacterial and atypical etiology of acute exacerbations of chronic obstructive pulmonary disease was investigated and the diagnostic techniques used were compared among 92 hospitalized patients. Materials & methods: Sputum specimens were investigated using culture and PCR, ...

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Association of matrix metalloproteinase-7A-181G variants with the risk of multiple sclerosis

01.12.2014 | Ziba Rahimi; Zohreh Rahimi; Fatemeh Mohammadi; Nazanin Razazian; Farid Najafi, Personalized Medicine, 2014

Aim: To investigate the influence of matrix metalloproteinase-7 (MMP-7) A-181G on the risk of multiple sclerosis (MS) and neurological disability. Patients & methods: The variants of MMP-7 were studied in 126 MS patients and 190 healthy controls. Results: The MMP-7 Gallele and AG+GG genotype ...

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Escherichia coli adaptation to the gut environment: a constant fight for survival

01.12.2014 | Isabel Gordo; Jocelyne Demengeot; Karina Xavier, Future Microbiology, 2014

Future Microbiology November 2014, Vol. 9, No. 11, Pages 1235-1238.

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Regulation of biofilm formation in Salmonella enterica serovar Typhimurium

01.12.2014 | Roger Simm; Irfan Ahmad; Mikael Rhen; Soazig Le Guyon; Ute Römling, Future Microbiology, 2014

ABSTRACT  In animals, plants and the environment, Salmonella enterica serovar Typhimurium forms the red dry and rough (rdar) biofilm characterized by extracellular matrix components curli and cellulose. With complex expression control by at least ten transcription factors, the bistably expressed ...

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Glioblastoma stem cells: new insights in therapeutic strategies

01.12.2014 | Nicolas Goffart; Matthias Dedobbeleer; Bernard Rogister, Future Neurology, 2014

ABSTRACT  Despite notable achievements in glioblastoma diagnosis and treatment, the prognosis of glioblastoma patients remains poor and reflects the failure of current therapeutic modalities. In this context, innovative therapeutic strategies have recently been developed to specifically target ...

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Ischemic stroke subtypes and the implications for stroke management

01.12.2014 | Antonino Tuttolomondo; Antonio Pinto, Future Neurology, 2014

Future Neurology November 2014, Vol. 9, No. 6, Pages 567-570.

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Molecular profiling and companion diagnostics: where is personalized medicine in cancer heading?

01.12.2014 | Mukesh Verma, Personalized Medicine, 2014

The goal of personalized medicine is to use the right drug at the right dose – with minimal or no toxicity – for the right patient at the right time. Recent advances in understanding cell biology and pathways, and in using molecular ‘omics’ technologies to diagnose cancer, offer a strategic ...

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