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3.537 Aktuelle Fachpublikationen von Future Medicine

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Platelet function testing as a biomarker for efficacy of antiplatelet drugs

14.07.2016 | Marie Lordkipanidzé; Derek So; Jean-François Tanguay, Biomarkers in Medicine, 2016

Despite the overwhelming evidence in support of the efficacy of dual antiplatelet therapy with aspirin and clopidogrel, it is also obvious that not all patients benefit from these drugs to the same extent. This interindividual variability in platelet responses may underlie clinical differences in ...

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Transplantation of a bacterial consortium ameliorates trinitrobenzenesulfonic acid-induced colitis and intestinal dysbiosis in rats

14.07.2016 | Ming Li; Zhenzhen Li; Shu Wen; Yinhui Liu; Ying Wang; Li Tang, Future Microbiology, 2016

Aim: To investigate the effects of a defined bacterial consortium on trinitrobenzenesulfonic acid (TNBS)-induced colitis and intestinal dysbiosis in rats. Materials & methods: Rats with TNBS-induced colitis were treated with ceftriaxone and/or a mixture of ten bacterial strains isolated from ...

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Performance of plasma calprotectin as a biomarker of early sepsis: a pilot study

14.07.2016 | Mikael Simm; Ewa Söderberg; Anders Larsson; Markus Castegren; Tom Nilsen; Mats Eriksson; Miklos Lipcsey, Biomarkers in Medicine, 2016

Aim: To determine the performance of plasma calprotectin as a marker of sepsis on intensive care unit (ICU) admission and as a marker of mortality day 30 post-ICU admission. Materials & methods: Consecutive ICU patients were allocated to: sepsis (n = 15), postoperative inflammation (n = 23) and ...

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Development of a biomarker scoring system for use in graft-versus-host disease

14.07.2016 | Anne S Renteria; John E Levine; James L Ferrara, Biomarkers in Medicine, 2016

Biomarkers in Medicine Ahead of Print.

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Relationship between microvessel density and cancer stem cells in tumor angiogenesis: a meta-analysis

14.07.2016 | Jiaojiao Lan; Jun Li; Xinxin Ju; Yang Zhou; Yan Qi; Yan Ren; Hong Zou; Lianghai Wang; Man Li; Lijuan Pang, Biomarkers in Medicine, 2016

Aim: Several studies have shown that cancer stem cells (CSCs) promote tumor angiogenesis and are involved in tumor growth. A meta-analysis was conducted to evaluate the association between cancer stem cell markers expression and microvessel density (MVD). Methods: Relevant literature was ...

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Drug repurposing for vascular dementia: overview and current developments

13.07.2016 | Hermann AM Mucke, Future Neurology, 2016

Antidementive drugs have made Alzheimer's disease a symptomatically treatable condition but have essentially bypassed vascular dementia. The complexity of its pathology, the variable pathognomonic manifestations, the absence of validated biomarkers and the continuum with Alzheimer's disease that ...

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The role of gender in glioblastoma: does it matter?

13.07.2016 | Enrico Franceschi; Alba A Brandes, Future Neurology, 2016

Future Neurology Ahead of Print.

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Targeting glia in human pain: challenges and opportunities

13.07.2016 | Parisa Gazerani, Future Neurology, 2016

Future Neurology Ahead of Print.

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hsa_circRNA_103636: potential novel diagnostic and therapeutic biomarker in Major depressive disorder

12.07.2016 | Xuelian Cui; Wei Niu; Lingming Kong; Mingjun He; Kunhong Jiang; Shengdong Chen; Aifang Zhong; Wanshuai Li; Jim Lu; L ..., Biomarkers in Medicine, 2016

Aim: This study aimed to determine whether circular RNA (circRNA) molecules in peripheral blood mononuclear cells (PBMCs) could be used as novel non-invasive biomarkers for major depressive disorder (MDD). Materials & methods: Differentially expressed circRNAs were screened using an Arraystar ...

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Studies of the role of a smart web for precision medicine supported by biobanking

05.07.2016 | Barry Robson; Srinidhi Boray, Personalized Medicine, 2016

Both the extraction of medical knowledge from data mining many patient records and from authoritative natural language text on the Internet are important for clinical decision support and biomedical research. The samples in biobanks represent a further kind of information repository of recognized ...

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