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2.635 Aktuelle Fachpublikationen von Future Medicine

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Potential role of tavaborole for the treatment of onychomycosis

01.12.2014 | Aditya K Gupta; Deanne Daigle, Future Microbiology, 2014

ABSTRACT  Systemic antifungal treatments are believed to be more effective than topicals for the treatment of onychomycosis; however, they are associated with more risks of adverse events. Tavaborole is the first member of a new class of antifungals that has been developed as a new topical nail ...

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Neuroimaging chronic pain: what have we learned and where are we going?

01.12.2014 | Katherine T Martucci; Pamela Ng; Sean Mackey, Future Neurology, 2014

ABSTRACT  Advances in neuroimaging have helped illuminate our understanding of how the brain works in the presence of chronic pain, which often persists with unknown etiology or after the painful stimulus has been removed and any wounds have healed. Neuroimaging has enabled us to make great ...

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An intimate link: two-component signal transduction systems and metal transport systems in bacteria

01.12.2014 | Kamna Singh; Dilani B Senadheera; Dennis G Cvitkovitch, Future Microbiology, 2014

ABSTRACT  Bacteria have evolved various strategies to contend with high concentrations of environmental heavy metal ions for rapid, adaptive responses to maintain cell viability. Evidence gathered in the past two decades suggests that bacterial two-component signal transduction systems (TCSTSs) ...

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Isolated unilateral hypoglossal nerve paralysis in a patient after spinal anesthesia: a case report

01.12.2014 | Septimiu Bucurescu, Future Neurology, 2014

ABSTRACT  In this paper, we describe the case of isolated unilateral hypoglossal nerve paralysis in a patient after spinal anesthesia. We also discuss the diagnosis, therapy and recovery prognosis in patients with hypoglossal nerve paralysis.

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Conference report from the International Congress on Infectious Diseases 2014: part one. 16th International Congress on Infectious Diseases, Cape Town, South Africa 2–5 April 2014

01.12.2014 | Hilda McLoughlin, Future Microbiology, 2014

ABSTRACT  The 16th International Congress on Infectious Diseases (ICID) was held in Cape Town this year, marking the return of the conference to Africa for the first time in 22 years. While infectious diseases such as malaria, tuberculosis and HIV – all still prevalent in the African healthcare ...

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Future of epilepsy treatment: integration of devices

01.12.2014 | Amanda F Van Straten; Barbara C Jobst, Future Neurology, 2014

ABSTRACT  The use of devices in the treatment of epilepsy is an emerging therapy for those patients whose seizures are not controlled by medications. This article will discuss current treatment options with devices for vagus nerve stimulation, deep brain stimulation and responsive ...

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Past, current and future approaches to querying MAPK pathway activation: status and clinical implications

01.12.2014 | Ken CN Chang; Matthew J Marton, Personalized Medicine, 2014

MAPK pathway activation related to cancer development has drawn a great deal of attention in the field of personalized medicine in recent years. Many different approaches and assays have been developed to query the activation of this pathway and to develop life-saving treatments. The goal of this ...

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Early cognitive decline in pituitary surgery: is nitrous oxide the culprit?

01.12.2014 | Tumul Chowdhury; Hemanshu Prabhakar; Parmod K Bithal; Bernhard Schaller; Hari H Dash, Future Neurology, 2014

ABSTRACT  Aim: Pituitary tumors have been found to produce cognitive dysfunctions predominantly related to memory and attention. There exists a potential interaction between surgical and anesthetic factors in producing cognitive changes. Therefore we aim to investigate the incidence of cognitive ...

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Nonamyloid PET biomarkers and Alzheimer's disease: current and future perspectives

01.12.2014 | Lucas Porcello Schilling; Antoine Leuzy; Eduardo Rigon Zimmer; Serge Gauthier; Pedro Rosa-Neto, Future Neurology, 2014

ABSTRACT  Recent advances in neurobiology and PET have helped redefine Alzheimer's disease (AD) as a dynamic pathophysiological process, clinically characterized by preclinical, mild cognitive impairment due to AD and dementia stages. Though a majority of PET studies conducted within these ...

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Seizures in children treated for a primary brain tumor: risk factors, evaluation and management

01.12.2014 | Emily A Gertsch; Nicole J Ullrich, Future Neurology, 2014

ABSTRACT  Seizures may be a presenting symptom of a brain tumor in childhood or can occur as a complication of treatment or subsequent effect occurring years after completion of therapy. Seizures create a number of therapeutic challenges and represent a significant comorbidity that results in ...

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