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3.783 Aktuelle Fachpublikationen von Future Medicine

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Update: looking beyond the 100,000 Genome Project

19.01.2017 | Susanne B Haga, Personalized Medicine, 2017

Personalized Medicine Ahead of Print.

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The pretreatment thrombocytosis may predict prognosis of patients with colorectal cancer: a systematic review and meta-analysis

18.01.2017 | Yong-hong Wang; Shao-jun Deng; Yong-dong Yang; Nan Yao; Jian-meng Zhao; Guang-tao Min; Jun Wang; Teng-fei Xu; Peng-y ..., Biomarkers in Medicine, 2017

Aim: Recently, several studies have reported that thrombocytosis may be associated with the poor prognosis of colorectal cancer (CRC). Nevertheless, their conclusions were still controversial. Results & methodology: We searched PubMed, Embase, Cochrane Library and Web of Science up to April 2016. ...

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Transformative biomarkers for drug-induced liver injury: are we there yet?

18.01.2017 | Daniel J Antoine; James W Dear, Biomarkers in Medicine, 2017

Biomarkers in Medicine Ahead of Print.

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High serum YKL-40 level positively correlates with coronary artery disease

18.01.2017 | Yan Jin; Jia-Ning Cao; Chun-Xia Wang; Qiu-Ting Feng; Xin-He Ye; Xin Xu; Cheng-Jian Yang, Biomarkers in Medicine, 2017

Aim: We investigated the predictive value of chitinase-like protein YKL-40 in coronary artery disease (CAD). Patients: Serum YKL-40 levels in 116 CAD patients and 82 healthy controls were analyzed. Severity of CAD was evaluated using Gensini scores. Spearman's correlation was used to evaluate the ...

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Metabolomics biomarkers for tuberculosis diagnostics: current status and future objectives

18.01.2017 | Ilse du Preez; Laneke Luies; Du Toit Loots, Biomarkers in Medicine, 2017

Numerous studies have contributed to our current understanding of the complex biology of pulmonary tuberculosis and subsequently provided solutions to its control or eradication. Metabolomics, a newcomer to the Omics research domain, has significantly contributed to this understanding by ...

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miRNA profiling for the early detection and clinical monitoring of diabetic kidney disease

18.01.2017 | Johanna K DiStefano, Biomarkers in Medicine, 2017

Biomarkers in Medicine Ahead of Print.

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Long noncoding RNA as an indicator differentiating schizophrenia from major depressive disorder and generalized anxiety disorder in nonpsychiatric hospital

16.01.2017 | Xuelian Cui; Wei Niu; Lingming Kong; Mingjun He; Kunhong Jiang; Shengdong Chen; Aifang Zhong; Qiaoli Zhang; Wanshuai ..., Biomarkers in Medicine, 2017

Aim: Depression and anxiety are common symptoms for schizophrenia (SZ) in the early onset. This study aimed to determine whether long noncoding RNAs (lncRNAs) can be indicators for diagnosing SZ in nonpsychiatric hospitals. Materials & methods: Three upregulated SZ lncRNAs, six downregulated ...

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Donors FMO3 polymorphisms affect tacrolimus elimination in Chinese liver transplant patients

13.01.2017 | Lei Ren; Mujian Teng; Tao Zhang; Xiaoqing Zhang; Bo Sun; Shengying Qin; Lin Zhong; Zhihai Peng; Junwei Fan, Pharmacogenomics, 2017

Aim: Flavin-containing monooxygenase (FMO) variants were potentially involved in tacrolimus metabolism in kidney transplantion. The influences of FMO3 genotypes on tacrolimus elimination in Chinese liver transplant patients remained unclear. Patients & methods: FMO3 SNPs and CYP3A5 rs776746 were ...

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Genetic variants associated with angiotensin-converting enzyme inhibitor-induced cough: a genome-wide association study in a Swedish population

13.01.2017 | Pär Hallberg; Matilda Persson; Tomas Axelsson; Marco Cavalli; Pia Norling; Hans-Erik Johansson; Qun-Ying Yue; Patrik ..., Pharmacogenomics, 2017

Aim: We conducted a genome-wide association study on angiotensin-converting enzyme inhibitor-induced cough and used our dataset to replicate candidate genes identified in previous studies. Patients & methods: A total of 124 patients and 1345 treated controls were genotyped using Illumina arrays. ...

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Introducing volume 14 of Personalized Medicine

21.12.2016 | Adam Price-Evans, Personalized Medicine, 2016

Personalized Medicine January 2017, Vol. 14, No. 1, Pages 1-3.

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