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3.435 Aktuelle Fachpublikationen von Future Medicine

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ProCA1.GRPR: a new imaging agent in cancer detection

13.04.2016 | Fan Pu; Shenghui Xue; Jenny J Yang, Biomarkers in Medicine, 2016

Biomarkers in Medicine Ahead of Print.

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Organism-wide studies into pathogenicity and morphogenesis in Talaromyces marneffei

13.04.2016 | Harshini Weerasinghe; Michael Payne; Sally Beard; Alex Andrianopoulos, Future Microbiology, 2016

Organism-wide approaches examining the genetic mechanisms controlling growth and proliferation have proven to be a powerful tool in the study of pathogenic fungi. For many fungal pathogens techniques to study transcription and protein expression are particularly useful, and offer insights into ...

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Reproducibility of circulating endothelial cell enumeration and activation in children and adolescents

13.04.2016 | Justin R Ryder; Michael J O’Connell; Kyle D Rudser; Claudia K Fox; Anna N Solovey; Robert P Hebbel; Aaron S Kelly, Biomarkers in Medicine, 2016

Introduction: We examined the reproducibility of circulating endothelial cells (CEC) enumeration and activation among youth. Methods: CECs from 151 youth were measured at baseline and 1 week follow-up. Enumeration of CEC in fresh whole blood was determined by direct assessment of buffy coat ...

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Identification of Apo B48 and other novel biomarkers in amyotrophic lateral sclerosis patient fibroblasts

13.04.2016 | Malathi Narayan; Kent W Seeley; Umesh K Jinwal, Biomarkers in Medicine, 2016

Aim: Amyotrophic lateral sclerosis (ALS) is a debilitating fatal neurodegenerative disorder. 90–95% of ALS cases are sporadic with no clear risk factors associated with the disease. Identification of biomarkers associated with ALS may lead to early detection and make it more amenable to ...

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Prognostic significance of overexpressed p16INK4A in esophageal squamous cell carcinoma: a meta-analysis

13.04.2016 | Lianghai Wang; Jing Li; Xiaodan Yu; Zhiyu Zhang; Lijuan Pang; Shugang Li; Jun Hou; Feng Li, Biomarkers in Medicine, 2016

Background: The prognostic value of p16INK4A in esophageal squamous cell carcinoma (ESCC) has been evaluated for several years although the results remain controversial. Methods: Various databases were systematically searched to identify studies published on the p16INK4A survival rate of ESCC ...

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Prognostic significance of whole blood viscosity estimated by de Simone’s formula in ST-elevation myocardial infarction

13.04.2016 | Elif Hande Ozcan Cetin; Mehmet Serkan Cetin; Uğur Canpolat; Selahattin Aydin; Dursun Aras; Serkan Topaloglu; Ahmet T ..., Biomarkers in Medicine, 2016

Background: We assessed the predictive value of estimated whole blood viscosity (WBV) in-hospital and long-term cardiovascular outcomes in patients with ST-elevation myocardial infarction (STEMI). Materials & methods: One thousand eight hundred and thirty-five STEMI patients were followed up for ...

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Prediction of micafungin area under the curve data by using peak concentration: applicability and utility in antifungal therapy

12.04.2016 | Nuggehally R Srinivas, Future Microbiology, 2016

Aim: To describe a predictive model to obtain the area under the plasma concentration versus time curve (AUC) for micafungin to aid in dosing strategies in pediatric patients. Methods: Using published pharmacokinetic data a linear regression model to describe the Cmax versus AUCtau was developed. ...

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Emerging tools for identification of arthropod vectors

12.04.2016 | Amina Yssouf; Lionel Almeras; Didier Raoult; Philippe Parola, Future Microbiology, 2016

The rapid and reliable identification of arthropod vector species is an essential component of the fight against vector-borne diseases. However, owing to the lack of entomological expertise required for the morphological identification method, development of alternative and complementary tools is ...

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Bioengineered probiotics as a new hope for health and diseases: an overview of potential and prospects

12.04.2016 | Manoj Kumar; Ashok Kumar Yadav; Vinod Verma; Birbal Singh; Gorakh Mal; Ravinder Nagpal; Rajkumar Hemalatha, Future Microbiology, 2016

Despite the use of microorganisms as therapeutics for over a century, the scientific and clinical admiration of their potential is a recent phenomenon. Genome sequencing and genetic engineering has enabled researchers to develop novel strategies, such as bioengineered probiotics or pharmabiotics, ...

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The potential role of trimethoprim-sulfamethoxazole in the treatment of drug-resistant tuberculosis

12.04.2016 | Juan Carlos Palomino; Anandi Martin, Future Microbiology, 2016

Tuberculosis (TB) remains a serious public health threat worsened by emerging drug resistance. Mycobacterium tuberculosis has become resistant not only to front-line drugs but also to second-line antimicrobials directed at drug-resistant TB. Renewed efforts are devoted for the development of new ...

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