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2.320 Aktuelle Fachpublikationen von Future Medicine


Potential biomarkers of autism

08.04.2014 | Hannah Wilson, Biomarkers in Medicine, 2014

Biomarkers in Medicine , March 2014, Vol. 8, No. 3, Pages 311-312.


Prognostic models in bipolar disorder: can the prediction of the long-term clinical course rely on the integration of clinical and molecular data?

08.04.2014 | Martina Pinna; Mirko Manchia, Biomarkers in Medicine, 2014

Biomarkers in Medicine , March 2014, Vol. 8, No. 3, Pages 371-374.


B-cell activating factor as a serological biomarker for polymyositis and dermatomyositis

08.04.2014 | Qing-Lin Peng; Xiao-Ming Shu; Dong-Xue Wang; Yan Wang; Xin Lu; Guo-Chun Wang, Biomarkers in Medicine, 2014

Aim: To investigate serum levels of B-cell activating factor (BAFF) in the patients with polymyositis (PM) and dermatomyositis (DM), and to systematically examine the association between serum BAFF levels and disease activity in PM/DM patients. Patients & methods: A cross-sectional analysis ...


News & Views … Biomarkers in Medicine

08.04.2014 | Biomarkers in Medicine, 2014

Biomarkers in Medicine , March 2014, Vol. 8, No. 3, Pages 379-382.


The search for circulating epilepsy biomarkers

08.04.2014 | Manu Hegde; Daniel H Lowenstein, Biomarkers in Medicine, 2014

Few would experience greater benefit from the development of biomarkers than those who suffer from epilepsy. Both the timing of individual seizures and the overall course of the disease are highly unpredictable, and the associated morbidity is considerable. Thus, there is an urgent need to ...


Reference intervals for urinary renal injury biomarkers KIM-1 and NGAL in healthy children

24.03.2014 | Stephen J McWilliam; Daniel J Antoine; Venkata Sabbisetti; Robin E Pearce; Andrea L Jorgensen; Yvonne Li ..., Biomarkers in Medicine, 2014

Aim: The aim of this study was to establish reference intervals in healthy children for two novel urinary biomarkers of acute kidney injury, kidney injury molecule-1 (KIM-1) and neutrophil gelatinase-associated lipocalin (NGAL). Materials & Methods: Urinary biomarkers were determined in samples ...


A logistic equation to determine the validity of tramadol from related gene polymorphisms and psychological factors

13.03.2014 | Qin Zhao; Jianguo Sun; Yifu Tao; Shukui Wang; Chunzhi Jiang; Yubing Zhu; Feng Yu; Junrong Zhu, Pharmacogenomics, 2014

Aim: This study was performed to develop an algorithm using polymorphisms of CYP2D6, p-gp, OPRM1, COMT and psychological variables to predict tramadol response in Chinese patients recovering from upper limb fracture internal fixation surgery. Methods: A total of 250 Han Chinese patients ...


Single nucleotide polymorphic macrophage cytokine regulation by Mycobacterium tuberculosis and drug treatment

13.03.2014 | Amit K Singh; Awadh Bihari Yadav; Rajiv Garg; Amit Misra, Pharmacogenomics, 2014

Aim: To investigate the survival of Mycobacterium tuberculosis in primary macrophages with SNPs affecting cytokine secretion under treatment with drugs in solution or microparticles. Materials & methods: Volunteers were typed for TNF (-308G/A), IL-10 (-1082A/G) and IL-4 (-590C/T). ...


Research Highlights: Genetic association of the NDUFS1 gene with antipsychotic-induced weight gain in schizophrenia

13.03.2014 | Eugene Lin; Hsien-Yuan Lane, Pharmacogenomics, 2014

Pharmacogenomics , March 2014, Vol. 15, No. 4, Pages 415-417.


MTHFR functional genetic variation and methotrexate treatment response in rheumatoid arthritis: a meta-analysis

13.03.2014 | Michael D Morgan; Nashwa Al-Shaarawy; Steve Martin; James I Robinson; Sarah Twigg; YEAR Consortium; Awadal ..., Pharmacogenomics, 2014

Aim: To date, functional MTHFR SNPs have been tested for their impact on low-dose methotrexate (MTX) response in small rheumatoid arthritis (RA) cohorts. We sought to test their effect in the single largest cohort studied to date, and undertook a meta-analysis utilizing stringent study inclusion ...


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