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2.597 Aktuelle Fachpublikationen von Future Medicine

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Antiadhesion agents against Gram-positive pathogens

18.11.2014 | Stella Cascioferro; Maria Grazia Cusimano; Domenico Schillaci, Future Microbiology, 2014

ABSTRACT  A fundamental step of Gram-positive pathogenesis is the bacterial adhesion to the host tissue involving interaction between bacterial surface molecules and host ligands. This review is focused on antivirulence compounds that target Gram-positive adhesins and on their potential ...

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Potential cytokine biomarkers in autism spectrum disorders

17.11.2014 | Destanie Rose; Paul Ashwood, Biomarkers in Medicine, 2014

Autism spectrum disorders (ASD) are complex neurodevelopmental disorders characterized by impairments in three core behavioral areas. As prevalence rates for ASD continue to rise there is also increasing interest in finding biomarkers associated with ASD. The use of biomarkers could help identify ...

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The use of molecular methods for the detection and identification of methicillin-resistant Staphylococcus aureus

17.11.2014 | Jari J Hirvonen, Biomarkers in Medicine, 2014

Methicillin-resistant Staphylococcus aureus (MRSA) is a major pathogen in many hospitals and long-term care facilities as well as in the community. To limit the spread of MRSA, early detection and proper treatment are essential. Because conventional culture as gold standard is time consuming, new ...

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DNA methylation of PITX2 predicts poor survival in men with prostate cancer

17.11.2014 | Nataša Vasiljević; Amar S Ahmad; Paul D Carter; Gabrielle Fisher; Daniel M Berney; Christopher S Foster; Jack Cuzick ..., Biomarkers in Medicine, 2014

Aim: We investigated if methylation of candidate genes can be useful for predicting prostate cancer (PCa) specific death. Patients & methods: Methylation of PITX2, WNT5a, SPARC, EPB41L3 and TPM4 was investigated in a 1:2 case–control cohort comprising 45 men with cancer of Gleason score ≤7 who ...

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Biomarker discovery for childhood infections: paving the way for a diagnostic revolution in the developing world

17.11.2014 | Miguel Lanaspa; Lola Madrid; Quique Bassat, Biomarkers in Medicine, 2014

Biomarkers in Medicine October 2014, Vol. 8, No. 9, Pages 1057-1060.

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Classical and new assays for detecting drug resistance in tuberculosis

17.11.2014 | Juan Carlos Palomino; Peter Vandamme; Anandi Martin, Biomarkers in Medicine, 2014

Tuberculosis is a public health concern worldwide. Particularly worrying is the emergence of severe forms of drug resistance, such as extensively drug resistant and totally drug resistant tuberculosis, with few treatment options for the afflicted patients. To avoid further spread of drug ...

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New biomarkers to fight urogenital schistosomiasis: a major neglected tropical disease

17.11.2014 | Mónica C Botelho; Mário Sousa, Biomarkers in Medicine, 2014

Biomarkers in Medicine October 2014, Vol. 8, No. 9, Pages 1061-1063.

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Methods of rapid diagnosis for the etiology of meningitis in adults

17.11.2014 | Nathan C Bahr; David R Boulware, Biomarkers in Medicine, 2014

Infectious meningitis may be due to bacterial, mycobacterial, fungal or viral agents. Diagnosis of meningitis must take into account numerous items of patient history and symptomatology along with regional epidemiology and basic cerebrospinal fluid testing (protein, etc.) to allow the clinician ...

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Advances in MRI biomarkers for the diagnosis of Alzheimer's disease

17.11.2014 | Elizabeth G Kehoe; Jonathan P McNulty; Paul G Mullins; Arun L W Bokde, Biomarkers in Medicine, 2014

With the prevalence of Alzheimer's disease (AD) predicted to increase substantially over the coming decades, the development of effective biomarkers for the early detection of the disease is paramount. In this short review, the main neuroimaging techniques which have shown potential as biomarkers ...

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Erratum

17.11.2014 | Biomarkers in Medicine, 2014

Biomarkers in Medicine October 2014, Vol. 8, No. 9, Pages 1184-1184.

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