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3.368 Aktuelle Fachpublikationen von Future Medicine

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Biopanel identifies expression status of targetable proteins in sinonasal melanoma

20.04.2016 | Lisa Grünmüller; Julia Thierauf; Stephanie E Weissinger; Christoph Bergmann; Agnes Bankfalvi; Johannes Veit; Thomas ..., Personalized Medicine, 2016

Background: Advanced stage at presentation, lack of BRAF-mutations and overall rarity pose unique challenges to the therapy and trial design in sinonasal melanoma. Methods: Here, we assessed the expression status of 12 proteins in two independent cohorts of sinonasal melanoma (n = 20). Results: ...


Prognostic value of plasma biomarkers in patients with acute coronary syndrome: a review of advances in the past decade

18.04.2016 | Richard Y Cao; Hongchao Zheng; Junjun Guo; Damian P Redfearn, Biomarkers in Medicine, 2016

Acute coronary syndrome (ACS), especially myocardial infarction, commonly known as a heart attack, is a serious life-threatening cardiovascular disease. Despite dramatic therapeutic advances, there have still been more than 20% patients with ACS suffering recurrent adverse cardiovascular events 3 ...


A novel marker of inflammation in patients with slow coronary flow: lymphocyte-to-monocyte ratio

18.04.2016 | Çağrı Yayla; Mehmet Kadri Akboğa; Kadriye Gayretli Yayla; Ahmet Göktuğ Ertem; Tolga Han Efe; Fatih Şen; Sefa Ünal; B ..., Biomarkers in Medicine, 2016

Aim: Recently, lymphocyte-to-monocyte ratio (LMR) has emerged as a new indirect marker of inflammation which is associated with adverse outcomes in oncology and cardiovascular diseases. The aim of the study was to evaluate the relationship between LMR and slow coronary flow (SCF). Patients & ...


Antibodies make analyses make answers

18.04.2016 | Jens P Goetze; Jens F Rehfeld, Biomarkers in Medicine, 2016

Biomarkers in Medicine Ahead of Print.


TNFAIP6 is a potential biomarker of disease activity in inflammatory bowel disease

18.04.2016 | Qiao Yu; Shenghong Zhang; Huiling Wang; Yingfan Zhang; Ting Feng; Baili Chen; Yao He; Zhirong Zeng; Minhu Chen, Biomarkers in Medicine, 2016

Aim: Ideal biomarkers are needed for evaluating the activity of inflammatory bowel disease (IBD). We aimed to investigate the value of TNFAIP6 as a biomarker. Materials & methods: Inflamed colonic samples and serum samples were collected from patients with Crohn's disease (CD), patients with ...


Antibiotic resistance: challenges and successes in respiratory infection

15.04.2016 | Sanjay Sethi; Jenny Bryan, Future Microbiology, 2016

European Respiratory Society Congress, Amsterdam, 26–30 September 2015, and CHEST 2015, Montréal, Canada, 24–28 October 2015 With approximately 50,000 deaths in the US and EU attributed to antibacterial resistance each year, together with several million days of hospital care[1], the need to ...


Melioidosis: where do we stand in the development of an effective vaccine?

15.04.2016 | Laura A Muruato; Alfredo G Torres, Future Microbiology, 2016

Future Microbiology Ahead of Print.


Prognostic value of FGF23 among patients with end-stage renal disease: a systematic review and meta-analysis

14.04.2016 | Hongliu Yang; Han Luo; Xi Tang; Xiaoxi Zeng; Yang Yu; Liang Ma; Ping Fu, Biomarkers in Medicine, 2016

Aims: Prognostic value of FGF23 in end-stage renal disease (ESRD) patients is controversial. A systematic review was conducted to quantify the association between elevated FGF23 and overall mortality among ESRD patients. Materials & Methods: MEDLINE, EMBASE, PubMed and reference lists were ...


Clinical RNA sequencing in oncology: where are we?

14.04.2016 | Gitte Pedersen; Tanya Kanigan, Personalized Medicine, 2016

Personalized Medicine Ahead of Print.


Detecting novel genes for low-density lipoprotein cholesterol in European population using bioinformatics analysis

14.04.2016 | Huan Zhang; Xing-Bo Mo; Tan Xu; Shu-Feng Lei; Yong-Hong Zhang, Personalized Medicine, 2016

Aim: The aim of this study was to identify related genes for low-density lipoprotein cholesterol and evaluate the functional relevance to provide evidences for prioritizing these genes. Materials & methods: We performed a gene-based association study in about 188,578 individuals. Furthermore, we ...


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