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2.969 Aktuelle Fachpublikationen von Future Medicine

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Exploratory analysis of candidate germline gene polymorphisms in breast cancer patients treated with neoadjuvant anthracycline-containing chemotherapy and associations with febrile neutropenia

20.08.2015 | A Charehbili; S de Groot; T van der Straaten; JJ Swen; H Pijl; H Gelderblom; CJH van de Velde; JWR Nortier; HJ Guche ..., Pharmacogenomics, 2015

Aim: SNPs may be associated with (side) effects of chemotherapy and may be useful as biomarkers to predict febrile neutropenia. Patients & methods: 187 DNA samples extracted from formalin-fixed paraffin-embedded tissue from patients with stage II/III HER2-negative breast cancer were genotyped. ...

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Extracellular vesicle microRNAs: biomarker discovery in various diseases based on RT-qPCR

19.08.2015 | Ying Liu; Qianjin Lu, Biomarkers in Medicine, 2015

In recent years, biomarker discovery based on extracellular microRNAs (miRNAs), especially exosome miRNAs, has drawn wide attention. While exosome isolation and identification technologies are increasingly sophisticated, the preanalytical process of exosome miRNAs seems to be no longer a crucial ...

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Adiponectin and leptin gene polymorphisms in patients with post-transplant diabetes mellitus

18.08.2015 | Maciej Romanowski; Violetta Dziedziejko; Agnieszka Maciejewska-Karlowska; Marek Sawczuk; Krzysztof Safranow; Leszek ..., Pharmacogenomics, 2015

Background: Post-transplant diabetes mellitus (PTDM) is a common metabolic complication after organ transplantation and may be associated with the use of calcineurin inhibitors (tacrolimus and cyclosporine). Leptin and adiponectin are adipokines and play an important role in the regulation of ...

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The future of stem cell therapy for stroke rehabilitation

14.08.2015 | Cesar V Borlongan; Jukka Jolkkonen; Olivier Detante, Future Neurology, 2015

Future Neurology August 2015, Vol. 10, No. 4, Pages 313-319.

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Stroke therapy: the potential of amniotic fluid-derived stem cells

14.08.2015 | Maya Elias; Jaclyn Hoover; Hung Nguyen; Stephanny Reyes; Christopher Lawton; Cesar V Borlongan, Future Neurology, 2015

Future Neurology August 2015, Vol. 10, No. 4, Pages 321-326.

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Intratumor heterogeneity and transcriptional profiling in glioblastoma: translational opportunities

14.08.2015 | Sara GM Piccirillo; Inmaculada Spiteri, Future Neurology, 2015

The study of phenotypic and genetic intratumor heterogeneity in glioblastoma is attracting a lot of attention. Recent studies have demonstrated that transcriptional profiling analysis can help interpret the complexity of this disease. Previously proposed molecular classifiers have been recently ...

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Neuroimaging in alcohol-use disorders: clinical implications and future directions

14.08.2015 | Omar M Alhassoon; Scott F Sorg; Mark J Stern; Matthew G Hall; Scott C Wollman, Future Neurology, 2015

Advances in clinical research have led to significant alterations in diagnostic criteria for alcohol-use disorders (AUD). Neuroimaging techniques are now being called upon to shed light on the validity and clinical utility of diagnostic criteria. For example, craving has recently been added to ...

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Neurological disorders, depression and inflammation: is there a common link?

14.08.2015 | Angelos Halaris, Future Neurology, 2015

To understand the origin of co-morbidity between neurological disorders and depressive illness, a multifactorial model is in order. Diverse approaches have been undertaken to elucidate the co-morbidity. Of these, the concept that inflammatory processes contribute to brain-related pathologies has ...

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New windows into the brain: technological advances in frontline neurologic diagnosis via the visual and oculomotor systems

14.08.2015 | Jorge C Kattah; John H Pula, Future Neurology, 2015

The 67th American Academy of Neurology (AAN) Annual Meeting, Washington, DC, USA, 18–25 April 2015 The 67th American Academy of Neurology (AAN) Annual Meeting took place in Washington, DC, in April 2015. The first day of the meeting featured an Integrated Neuroscience Session focusing on ...

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Alzheimer's disease: a novel application for deep-brain stimulation?

14.08.2015 | Tejas Sankar, Future Neurology, 2015

Future Neurology August 2015, Vol. 10, No. 4, Pages 297-300.

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