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2.487 Aktuelle Fachpublikationen von Future Medicine

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Inflammatory cytokines kinetics define the severity and phase of nephropathia epidemica

14.10.2014 | Asia A Baigildina; Svetlana F Khaiboullina; Ekaterina V Martynova; Vladimir A Anokhin; Vincent C Lombardi; Albert A ..., Biomarkers in Medicine, 2014

Aims: Nephropathia epidemica (NE) is a form of hemorrhagic fever with renal syndrome associated with the Puumala virus species of Hantavirus. The pathogenesis of NE is not well understood; therefore, investigating the inflammatory cytokine response to infection may provide useful knowledge in ...

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Circulating nucleosomes: a new addition to the personalized medicine toolkit

13.10.2014 | Stefan Holdenrieder, Personalized Medicine, 2014

Dr Stefan Holdenrieder is senior physician at the Institute of Clinical Chemistry and Clinical Pharmacology of the University Hospital Bonn, Germany. He is an expert in the field of circulating tumor biomarkers and particularly circulating nucleosomes. He has conducted numerous clinical studies ...

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Highlights from the field of biomarkers in melanoma

13.10.2014 | Hardev Pandha, Biomarkers in Medicine, 2014

Biomarkers in Medicine August 2014, Vol. 8, No. 7, Pages 917-919.

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An assessment of clinician and researcher needs for support in the era of genomic medicine

13.10.2014 | Sarah K Savage; Sonja I Ziniel; Joan Stoler; David M Margulies; Ingrid A Holm; Catherine A Brownstein, Personalized Medicine, 2014

Aim: To assess clinicians’ and researchers’ past, current and anticipated future use of next-generation sequencing (NGS) and anticipated needs for support. Materials&methods: A web-based survey was conducted at Boston Children’s Hospital. Results: Many clinicians anticipate that they will use ...

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Benefits and burdens of newborn screening: public understanding and decision-making

13.10.2014 | Stuart G Nicholls; Brenda J Wilson; Holly Etchegary; Jamie C Brehaut; Beth K Potter; Robin Hayeems; Pranesh Chakrabo ..., Personalized Medicine, 2014

In this article we review the literature regarding the public understanding of the potential benefits and burdens of expanded newborn bloodspot screening. We draw attention to broadened notions of benefit that go beyond early identification of asymptomatic individuals and interventions to reduce ...

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Biomarkers in pediatric heart disease

13.10.2014 | Hythem Nawaytou; Harold S Bernstein, Biomarkers in Medicine, 2014

A biomarker is a characteristic that can be used as an indicator of a biological state. A biomarker can be a clinical observation, laboratory test or an imaging parameter. In this review, we discuss the use of biomarkers in differentiating cardiac from noncardiac disease; predicting the prognosis ...

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Overcoming immune system evasion by personalized immunotherapy

13.10.2014 | Kevin C Soares; Lei Zheng; Nita Ahuja, Personalized Medicine, 2014

Personalized Medicine August 2014, Vol. 11, No. 6, Pages 561-564.

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Targeted next-generation sequencing: the clinician’s stethoscope for genetic disorders

13.10.2014 | Jan Haas; Ioana Barb; Hugo A Katus; Benjamin Meder, Personalized Medicine, 2014

Genetic biomarkers are crucial for diagnosis, guiding of treatments and estimation of prognosis. In the past, clinical genetic diagnostics was limited by the sequencing information gained from selected exons and single genes. For genetically heterogeneous diseases, such as cardiomyopathies, where ...

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Biomarkers for diagnosis and prognostic stratification of aortic dissection: challenges and perspectives

13.10.2014 | Fulvio Morello; Pavel Piler; Miroslav Novak; Peter Kruzliak, Biomarkers in Medicine, 2014

Aortic dissection (AD) is a severe vascular disease associated with major morbidity and mortality. The diagnosis of AD requires the performance of urgent aortic imaging exams such as computed tomography angiography, but the decision to perform these exams now essentially relies on clinical ...

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Association of FSH with metabolic syndrome in postmenopausal women: a comparison with CRP, adiponectin and leptin

13.10.2014 | Anna Stefanska; Irena Ponikowska; Malgorzata Cwiklinska-Jurkowska; Grazyna Sypniewska, Biomarkers in Medicine, 2014

Aim: The aim of this study was to evaluate the usefulness of follicle-stimulating hormone (FSH) determination in the postmenopausal women with metabolic syndrome (MetS) in a comparative analysis with biomarkers such as C-reactive protein (CRP), adiponectin, leptin and leptin-to-adiponectin ratio ...

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