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2.382 Aktuelle Fachpublikationen von Elsevier

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Support vector machine with a Pearson VII function kernel for discriminating halophilic and non-halophilic proteins

20.05.2013 | Author(s): Guangya Zhang , Ge Huihua, Computational Biology and Chemistry, 2013

Publication date: Available online 17 May 2013 Source:Computational Biology and Chemistry Author(s): Guangya Zhang , Ge Huihua Understanding of proteins adaptive to hypersaline environment and identifying them is a challenging task and would help to design stable proteins. Here, we ...

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Prediction and verification of microRNAs related to proline accumulation under drought stress in potato

20.05.2013 | Author(s): Jiangwei Yang , Ning Zhang , Congyu Ma , Yun Qu , Huaijun Si , Di Wang, Computational Biology and Chemistry, 2013

Publication date: Available online 14 May 2013 Source:Computational Biology and Chemistry Author(s): Jiangwei Yang , Ning Zhang , Congyu Ma , Yun Qu , Huaijun Si , Di Wang Proline is an important osmotic adjusting material greatly accumulated under drought stress and can help ...

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Two-in-One antibodies with dual action Fabs

20.05.2013 | Author(s): Charles Eigenbrot , Germaine Fuh, Current Opinion in Chemical Biology, 2013

Publication date: Available online 14 May 2013 Source:Current Opinion in Chemical Biology Author(s): Charles Eigenbrot , Germaine Fuh Mechanisms and biological roles of antibody multi-specificity are topics of high interest. Evidence of conformational flexibility in antigen-combining ...

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Innovation in academic chemical screening: filling the gaps in chemical biology

20.05.2013 | Author(s): Samuel A Hasson , James Inglese, Current Opinion in Chemical Biology, 2013

Publication date: Available online 14 May 2013 Source:Current Opinion in Chemical Biology Author(s): Samuel A Hasson , James Inglese Academic screening centers across the world have endeavored to discover small molecules that can modulate biological systems. To increase the reach of ...

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Inhibitors of BACE for treating Alzheimer's disease: a fragment-based drug discovery story

20.05.2013 | Author(s): Andrew Stamford , Corey Strickland, Current Opinion in Chemical Biology, 2013

Publication date: Available online 14 May 2013 Source:Current Opinion in Chemical Biology Author(s): Andrew Stamford , Corey Strickland Several fragment-based methods have been applied to the discovery of new lead sources for inhibitors of BACE1, an important therapeutic target for ...

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Advances in microalgae engineering and synthetic biology applications for biofuel production

20.05.2013 | Author(s): Javier A Gimpel , Elizabeth A Specht , D Ryan Georgianna , Stephen P Mayfield, Current Opinion in Chemical Biology, 2013

Publication date: Available online 16 May 2013 Source:Current Opinion in Chemical Biology Author(s): Javier A Gimpel , Elizabeth A Specht , D Ryan Georgianna , Stephen P Mayfield Among the technologies being examined to produce renewable fuels, microalgae are viewed by many in the ...

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Engineering fatty acid biosynthesis in microalgae for sustainable biodiesel

20.05.2013 | Author(s): Jillian L. Blatti , Jennifer Michaud , Michael D. Burkart, Current Opinion in Chemical Biology, 2013

Publication date: Available online 14 May 2013 Source:Current Opinion in Chemical Biology Author(s): Jillian L. Blatti , Jennifer Michaud , Michael D. Burkart Microalgae are a promising feedstock for biodiesel and other liquid fuels due to their fast growth rate, high lipid yields, ...

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Next generation therapeutics

20.05.2013 | Author(s): Paul J Carter , Daria Hazuda , James A Wells, Current Opinion in Chemical Biology, 2013

Publication date: Available online 14 May 2013 Source:Current Opinion in Chemical Biology Author(s): Paul J Carter , Daria Hazuda , James A Wells

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The human microbiome is a source of therapeutic drug targets

20.05.2013 | Author(s): Bret D Wallace , Matthew R Redinbo, Current Opinion in Chemical Biology, 2013

Publication date: Available online 13 May 2013 Source:Current Opinion in Chemical Biology Author(s): Bret D Wallace , Matthew R Redinbo It was appreciated early in drug discovery that the microbiota play an important role in the efficacy of therapeutic compounds. Indeed, the first ...

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A P-gp vesicular transport inhibition assay – Optimization and validation for drug–drug interaction testing

20.05.2013 | Author(s): Krisztina Herédi-Szabó , Johan E. Palm , Tommy B. Andersson , Ákos Pál , Dóra Méhn , Erzsébet Beéry ..., European Journal of Pharmaceutical Science, 2013

Publication date: Available online 15 May 2013 Source:European Journal of Pharmaceutical Sciences Author(s): Krisztina Herédi-Szabó , Johan E. Palm , Tommy B. Andersson , Ákos Pál , Dóra Méhn , Erzsébet Beéry , Katalin Tauber Jakab , Márton Jani , Peter Krajcsi Accurate ...

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