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1.192 Aktuelle Fachpublikationen aus der Branche Medizin

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Pregnancy as a critical window for blood pressure regulation in mother and child: programming and reprogramming

28.04.2016 | Nina D. Paauw, Bas B. van Rijn, A. Titia Lely, Jaap A. Joles, Acta Physiologica, 2016

Abstract Pregnancy is a critical time for long‐term blood pressure regulation in both mother and child. Pregnancies complicated by placental insufficiency, resulting in preeclampsia and intrauterine growth restriction, are associated with a threefold increased risk of the mother to develop ...

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Idiopathic intracranial hypertension, hormones, and 11ß-hydroxysteroid dehydrogenases

19.04.2016 | Journal of Pain Research, 2016

Markey KA, Uldall M, Botfield H, Cato LD, Miah MAL, Hassan-Smith G, Jensen RH, Gonzalez AM, Sinclair AJ

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Risks of atrial fibrillation and death at discharge after thrombolysis in stroke patients: Northumbrian Sentinel Stroke Audit, 2013–2015

13.04.2016 | I. Shiue, Acta Neurologica Scandinavica, 2016

Background The aim of this study was to examine risks of atrial fibrillation and death at discharge in stroke patients treated with thrombolysis in a subregional setting covering full calendar years with a clear study catchment drawn serving as a confirmatory statistical analysis from the ...

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Exaggerated hemodynamic and neural responses to involuntary contractions induced by whole body vibration in normotensive obese vs. lean women

09.04.2016 | Konstantina Dipla, Dimitra Kousoula, Andreas Zafeiridis, Konstantina Karatrantou, Michalis G. Nikolaidis, Antonios K ..., Experimental Physiology, 2016

In obesity, the exaggerated blood pressure (BP) response to exercise is linked to hypertension, yet the mechanisms are not fully elucidated. In this study, we aimed at examining whether involuntary mechanical oscillations, induced by whole‐body‐vibration (WBV), elicit greater hemodynamic ...

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Plasma uric acid concentrations and risk of ischaemic stroke in women

09.04.2016 | M. C. Jiménez, G. C. Curhan, H. K. Choi, J. P. Forman, K. M. Rexrode, European Journal of Neurology, 2016

Background and purpose Elevated plasma uric acid has been inconsistently associated with an increased risk of total stroke; however, data are sparse amongst women. The association between plasma uric acid concentrations and ischaemic stroke amongst women was examined and the effect ...

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The anti‐hypertensive drug prazosin inhibits glioblastoma growth via the PKCδ‐dependent inhibition of the AKT pathway

04.04.2016 | Suzana Assad Kahn, Silvia Lima Costa, Sharareh Gholamin, Ryan T Nitta, Luiz Gustavo Dubois, Marie Fève, Maria Zeniou ..., EMBO Molecular Medicine, 2016

Abstract A variety of drugs targeting monoamine receptors are routinely used in human pharmacology. We assessed the effect of these drugs on the viability of tumor‐initiating cells isolated from patients with glioblastoma. Among the drugs targeting monoamine receptors, we identified prazosin, ...

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eNOS|[sol]|iNOS and endoplasmic reticulum stress-induced apoptosis in the placentas of patients with preeclampsia

31.03.2016 | L Du; F He; L Kuang; W Tang; Y Li; D Chen, Journal of Human Hypertension, 2016

eNOS/iNOS and endoplasmic reticulum stress-induced apoptosis in the placentas of patients with preeclampsia Journal of Human Hypertension advance online publication, March 31 2016. doi:10.1038/jhh.2016.17 Authors: L Du, F He, L Kuang, W Tang, Y Li & D Chen

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Left Atrial Geometry Improves Risk Prediction of Thromboembolic Events In Patients with Atrial Fibrillation

30.03.2016 | FELIPE BISBAL, FEDERICO GÓMEZ‐PULIDO, PILAR CABANAS‐GRANDÍO, NAZEM AKOUM, MIREIA CALVO, DAVID ANDREU BENG, SUSANNA P ..., Journal of Cardiovascular Electrophysiology, 2016

Background Left atrial (LA) sphericity (LASP) is a new remodeling parameter based on LA shape analysis, with independent predictive value for recurrence after atrial fibrillation (AF) ablation. Objectives To evaluate the association between LASP and thromboembolic events (TE) in ...

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Genetic variants in adiponectin and blood pressure responses to dietary sodium or potassium interventions: a family-based association study

24.03.2016 | C Chu; Y Wang; K-y Ren; D-y Yan; T-s Guo; W-l Zheng; Z-y Yuan; J-j Mu, Journal of Human Hypertension, 2016

Genetic variants in adiponectin and blood pressure responses to dietary sodium or potassium interventions: a family-based association study Journal of Human Hypertension advance online publication, March 24 2016. doi:10.1038/jhh.2016.5 Authors: C Chu, Y Wang, K-y Ren, D-y Yan, T-s ...

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A20 deficiency leads to angiogenesis of pulmonary artery endothelial cells through stronger NF‐κB activation under hypoxia

17.03.2016 | Jing Li, Linlin Zhang, Yueming Zhang, Ying Liu, Hongyue Zhang, Liuping Wei, Tingting Shen, Chun Jiang, Daling Zhu, Journal of Cellular and Molecular Medicine, 2016

Abstract A20 is a zinc finger protein associated with hypoxia. As chronic hypoxia is responsible for intimal hyperplasia and disordered angiogenesis of pulmonary artery, which are histological hallmarks of pulmonary artery hypertension, we intended to explore the role of A20 in angiogenesis of ...

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