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60.248 Aktuelle Fachpublikationen aus der Branche Medizin

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BJD Editor's Choice

01.05.2015 | Journal of Investigative Dermatology, 2015

BJD Editor's Choice Journal of Investigative Dermatology 135, 1209 (May 2015). doi:10.1038/jid.2015.97

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Cells to Surgery Quiz: May 2015

01.05.2015 | Fleta N Bray; Mohammed Alsaidan; Leyre Falto-Aizpurua; Brian J Simmons; Mohammad-Ali Yazdani Abyaneh; Robert D Griff ..., Journal of Investigative Dermatology, 2015

Cells to Surgery Quiz: May 2015 Journal of Investigative Dermatology 135, e13 (May 2015). doi:10.1038/jid.2015.101 Authors: Fleta N Bray, Mohammed Alsaidan, Leyre Falto-Aizpurua, Brian J Simmons, Mohammad-Ali Yazdani Abyaneh, Robert D Griffith & Keyvan Nouri

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Editors' Picks

01.05.2015 | Journal of Investigative Dermatology, 2015

Editors' Picks Journal of Investigative Dermatology 135, 1210 (May 2015). doi:10.1038/jid.2015.98

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How MicroRNAs Modify Protein Production

01.05.2015 | Jessica L Feig; Keith M Giles; Iman Osman; Andrew G Franks, Journal of Investigative Dermatology, 2015

How MicroRNAs Modify Protein Production Journal of Investigative Dermatology 135, e32 (May 2015). doi:10.1038/jid.2015.99 Authors: Jessica L Feig, Keith M Giles, Iman Osman & Andrew G Franks

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Regulation of T cell development by c-Cbl: essential role of Lck

01.05.2015 | Y. Jeffrey Chiang; Richard J. Hodes, International Immunology, 2015

A canonical pre-TCR/TCR signaling pathway critical for thymic T cell development involves sequential phosphorylation and signaling through Lck, Zap70, Lat and Slp76. However, we and others have previously reported that genomic deletion of c-Cbl (Cbl) partially or completely reverses the defects ...

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Bestrophin‐3 is differently expressed in normal and injured mouse glomerular podocytes

25.04.2015 | Veronika Golubinskaya, Johannes Elvin, Kerstin Ebefors, Helena Gustafsson, Carina Mallard, Jenny Nyström, Holger Nilsson, Acta Physiologica, 2015

Abstract Aim Bestrophins are putative calcium‐activated chloride channels. Recently cell‐protective functions for Bestrophin‐3 (Best3) were proposed. Best3 exists in different splice variants. We have here examined expression, alternative splicing and localization of Best3 in mouse podocytes ...

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Validation of the composite autonomic symptom scale 31 (COMPASS‐31) in patients with and without small fiber polyneuropathy

23.04.2015 | R. Treister, K. O'Neil, H. M. Downs, A. L. Oaklander, European Journal of Neurology, 2015

Background and purpose The recently developed composite autonomic symptom score 31 (COMPASS‐31) is a questionnaire that assess symptoms of dysautonomia. It was distilled from the well‐established Autonomic Symptom Profile questionnaire. COMPASS‐31 has not yet been externally validated. To do ...

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Spinal triage predictors of success

23.04.2015 | Journal of Pain Research, 2015

Bath B, Lovo Grona S

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The hallmarks of cancer: relevance to the pathogenesis of polycystic kidney disease

23.04.2015 | Tamina Seeger-Nukpezah; Daniel M. Geynisman; Anna S. Nikonova; Thomas Benzing; Erica A. Golemis, Nature Clinical Practice Nephrology, 2015

Autosomal dominant polycystic kidney disease (ADPKD) is a progressive inherited disorder in which renal tissue is gradually replaced with fluid-filled cysts. Interestingly, improved understanding of the signalling and pathological derangements characteristic of ADPKD has revealed marked ...

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Evidence for eomesodermin‐expressing innate‐like CD8+ kir/nkg2a+ t cells in human adults and cord blood samples

22.04.2015 | Florence Jacomet, Emilie Cayssials, Sara Basbous, Anaïs Levescot, Nathalie Piccirilli, Deborah Desmier, Aurélie Robi ..., European Journal of Immunology, 2015

Polyclonal CD8+ T cells, with a marked innate/memory phenotype, high eomesodermin (Eomes) expression and the capacity to generate IFN‐γ rapidly without prior exposure to antigen, have been described in mice. However, even though a pool of human CD8+ T cells expressing killer Ig‐like receptors ...

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