Synthesis and Biological Activities of Topopyrones

PepFect14 Peptide Vector for Efficient Gene Delivery in Cell Cultures

The successful applicability of gene therapy approaches will heavily rely on the development of efficient and safe nonviral gene delivery vectors, for example, cell-penetrating peptides (CPPs). CPPs can condense oligonucleotides and plasmid DNA (pDNA) into nanoparticles, thus allowing the t ... mehr

Dendrimeric Bowties Featuring Hemispheric-Selective Decoration of Ligands for microRNA-Based Therapy

Dendrimers feature a defined number of terminal groups that may bind RNA or be functionalized with bioactive molecules. These competing uses of terminal groups may create an impasse if the requisite density of ligands depletes the number of terminal groups for binding sufficient RNA, or vic ... mehr

Bioinspired and Highly Oriented Clay Nanocomposites with a Xyloglucan Biopolymer Matrix: Extending the Range of Mechanical and Barrier Properties

The development of clay bionanocomposites requires processing routes with nanostructural control. Moreover, moisture durability is a concern with water-soluble biopolymers. Here, oriented bionanocomposite coatings with strong in-plane orientation of clay platelets are for the first time pre ... mehr

American Chemical Society Publications

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