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A cross-platform metabolomics workflow for volume-restricted tissue samples: application to an animal model for polycystic kidney disease

Metabolic profiling provides an unbiased view of the physiological status of an organism as a “function” of the metabolic composition of a measured sample. Here, we propose a simple LC-MS based workflow for metabolic profiling volume-restricted samples, namely 20 µm-thickness histological sections of mouse k

Autoren:   Elena Sánchez-López; Hester Happé; Evelyne Steenvoorden; Antonio L Crego; maria luisa marina; Dorien Peters; Oleg A Mayboroda
Journal:   Molecular BioSystems
DOI:   10.1039/C7MB00245A
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