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Le cancer de la prostate est une maladie grandement affectée par le style de vie, particulièrement la diète, et il est plus fréquent aux États-Unis et dans les pays européens comparativement à l'Asie de sud et de l'est. Parmi les nombreuses causes et facteurs de risques connus, la nutrition ... mehr
Otitis media with effusion (OME) is the most common cause of hearing loss in children and tympanostomy to alleviate the condition remains the commonest surgical intervention in children in the developed world. Chronic and recurrent forms of OM are known to have a very significant genetic c ... mehr
Small intestinal epithelial cells (sIECs) have a significant share in whole body metabolism as they perform enzymatic digestion and absorption of nutrients. Furthermore, the diet plays a key role in a number of complex diseases including obesity and diabetes. The impact of diet and altered ... mehr
Endolysins are bacteriophage enzymes that lyse their bacterial host for phage progeny release. They commonly contain an N-terminal catalytic domain that hydrolyzes bacterial peptidoglycan (PG) and a C-terminal cell wall-binding domain (CBD) that confers enzyme localization to the PG substr ... mehr
Visual refractive errors (REs) are complex genetic traits with a largely unknown etiology. To date, genome-wide association studies (GWASs) of moderate size have identified several novel risk markers for RE, measured here as mean spherical equivalent (MSE). We performed a GWAS using a tota ... mehr
Otitis media with effusion (OME) is the most common cause of hearing loss in children and tympanostomy to alleviate the condition remains the commonest surgical intervention in children in the developed world. Chronic and recurrent forms of OM are known to have a very significant genetic c ... mehr
Small intestinal epithelial cells (sIECs) have a significant share in whole body metabolism as they perform enzymatic digestion and absorption of nutrients. Furthermore, the diet plays a key role in a number of complex diseases including obesity and diabetes. The impact of diet and altered ... mehr
Visual refractive errors (REs) are complex genetic traits with a largely unknown etiology. To date, genome-wide association studies (GWASs) of moderate size have identified several novel risk markers for RE, measured here as mean spherical equivalent (MSE). We performed a GWAS using a tota ... mehr
Large intronic expansions of the triplet-repeat sequence (GAA.TTC) cause transcriptional repression of the Frataxin gene (FXN) leading to Friedreich's ataxia (FRDA). We previously found that GAA-triplet expansions stimulate heterochromatinization in vivo in transgenic mice. We report here ... mehr
Mutations in Parkin or PINK1 are the most common cause of recessively inherited parkinsonism. Parkin and PINK1 function in a conserved mitochondrial quality control pathway, in which PINK1, a putative mitochondrial kinase, directs Parkin, a cytosolic E3 ubiquitin ligase, selectively to dys ... mehr
ABSTRACT Recently, a new subgroup of Gaucher's disease type 2 with early manifestations during fetal life has been reported. This report illustrates the diversity of fetal malformations observed in this entity, also called perinatal lethal Gaucher's disease, and, because of phenotypic v ... mehr
ABSTRACT Objectives To evaluate whether a relationship exists between season at conception and occurrence of Isolated Spina Bifida (ISB). Study design All fetuses with prenatal diagnosis of ISB were analyzed according to date of conception. We compared the seasonal rates of con ... mehr
ABSTRACT Objective This study aims to evaluate the utility of first trimester cervical ultrasonography in predicting preterm delivery by separate analysis of measurements of cervical and isthmus length. Methods This is a cohort study based on data collected prospectively on sin ... mehr
ABSTRACT Objective To compare the angio‐architecture of monochorionic placentas of spontaneous twin anaemia‐polycythemia sequence (TAPS) with placenta of Twin to Twin Transfusion Syndrome (TTTS) with residual anastomoses after laser coagulation and placentas of uncomplicated monochori ... mehr
ABSTRACT Objectives The aim of our study was to evaluate placental three‐dimensional power Doppler indices in diabetic pregnancies in the second and third trimester and to compare them with those of the normal controls. Methods Placental vascularisation of pregnant women were d ... mehr
Inside Lab Invest Laboratory Investigation 93, 624 (June 2013). doi:10.1038/labinvest.2013.68 mehr
Inside Lab Invest Laboratory Investigation 93, 500 (May 2013). doi:10.1038/labinvest.2013.58 mehr
Inside Lab Invest Laboratory Investigation 93, 376 (April 2013). doi:10.1038/labinvest.2013.49 mehr
Methods for defining distinct bioenergetic profiles in platelets, lymphocytes, monocytes, and neutrophils, and the oxidative burst from human blood Laboratory Investigation advance online publication, March 25 2013. doi:10.1038/labinvest.2013.53 Authors: Balu K Chacko, Phili ... mehr
Inside Lab Invest Laboratory Investigation 93, 266 (March 2013). doi:10.1038/labinvest.2013.11 mehr
Publication date: Available online 5 June 2013 Source:European Journal of Pharmaceutical Sciences Author(s): Su-A Kim , Sung-Hwan Kim , Hoo-Kyun Choi , Hyo-Kyung Han The present study aimed to evaluate the effect of curcumin-loaded solid dispersion on the pharmacokinetics of saqui ... mehr
Publication date: Available online 4 June 2013 Source:European Journal of Pharmaceutical Sciences Author(s): Susanna Nybond , Matti Karp , Päivi Tammela This report describes the optimization and validation of an antimicrobial assay based on the genetically modified bacterial strai ... mehr
Publication date: Available online 7 June 2013 Source:European Journal of Pharmaceutical Sciences Author(s): Gemma Manich , Itsaso Cabezón , Jaume del Valle , Joaquim Duran-Vilaregut , Antoni Camins , Mercè Pallàs , Carme Pelegrí , Jordi Vilaplana One strategy used to transpor ... mehr
Publication date: Available online 6 June 2013 Source:European Journal of Pharmaceutical Sciences Author(s): Hua Yang , Ya Liu , Xiao-Lan Lu , Xiao-Hui Li , Hai-Gang Zhang The Gαq protein carboxyl terminus imitation polypeptide (GCIP)-27 has been shown to affect cardiac hypertrop ... mehr
Publication date: Available online 5 June 2013 Source:European Journal of Pharmaceutical Sciences Author(s): Manal A. Abbas , Ahmad M. Disi , Mutasem O. Taha Endometriosis is one of the most frequent diseases in gynecology. Currently available medical therapies for this disease are ... mehr
Kocks JWH, van den Berg JWK, Kerstjens HAM, Uil SM, Vonk JM, de Jong YP, Tsiligianni IG, van der Molen T mehr
Özün Özbay P, Ekinci T, Yiğit S, Yavuzcan A, Uysal S, Soylu F, Cakalogaoglu F mehr
Liu N, Sheng X, Liu Y, Zhang X, Yu J mehr
Perelman M, Leake S mehr
Chen ZW, Luo QQ, Jian H, Zhou Z, Cheng BJ, Lu S, Liao ML mehr
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