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Aktuelle Fachpublikationen

A novel BCMA|[sol]|CD3 bispecific T-cell engager for the treatment of multiple myeloma induces selective lysis in vitro and in vivo

A novel BCMA/CD3 bispecific T-cell engager for the treatment of multiple myeloma induces selective lysis in vitro and in vivo Leukemia advance online publication, January 13 2017. doi:10.1038/leu.2016.388 Authors: S Hipp, Y-T Tai, D Blanset, P Deegen, J Wahl, O Thomas, B Ratte ... mehr

A TLR7 agonist enhances the antitumor efficacy of obinutuzumab in murine lymphoma models via NK cells and CD4 T cells

A TLR7 agonist enhances the antitumor efficacy of obinutuzumab in murine lymphoma models via NK cells and CD4 T cells Leukemia advance online publication, January 3 2017. doi:10.1038/leu.2016.352 Authors: E J Cheadle, G Lipowska-Bhalla, S J Dovedi, E Fagnano, C Klein, J Honeyc ... mehr

Masked hypertension|[mdash]|what lies ahead|[quest]|

Masked hypertension—what lies ahead? Journal of Human Hypertension 31, 545 (September 2017). doi:10.1038/jhh.2017.11 Authors: D E Anstey & D Shimbo mehr

Intracellular directed evolution of proteins from combinatorial libraries based on conditional phage replication

Nature Protocols 12, 1830 (2017). doi:10.1038/nprot.2017.084 Authors: Andreas K Brödel, Alfonso Jaramillo & Mark Isalan Directed evolution is a powerful tool to improve the characteristics of biomolecules. Here we present a protocol for the intracellular evolution of prot ... mehr

Masked hypertension|[mdash]|what lies ahead|[quest]|

Masked hypertension—what lies ahead? Journal of Human Hypertension, Published online: 9 August 2017; doi:10.1038/jhh.2017.11 mehr

Alle Fachpublikationen

Elastin-PLGA Hybrid Electrospun Nanofiber Scaffolds for Salivary Epithelial Cell Self-Organization and Polarization

Publication date: Available online 8 August 2017 Source:Acta Biomaterialia Author(s): Zahraa I. Foraida, Tim Kamaldinov, Deirdre A. Nelson, Melinda Larsen, James Castracane Development of electrospun nanofibers that mimic the structural, mechanical and biochemical properties ... mehr

Structural, tribological, and mechanical properties of the hind leg joint of a jumping insect: Using katydids to inform bioinspired lubrication systems

Publication date: Available online 9 August 2017 Source:Acta Biomaterialia Author(s): Jun Kyun Oh, Spencer T. Behmer, Richelle Marquess, Cengiz Yegin, Ethan A. Scholar, Mustafa Akbulut This study investigates the structural properties of the hind leg femur-tibia joint in a ... mehr

The synergistic effects of Sr and Si bioactive ions on osteogenesis, osteoclastogenesis and angiogenesis for osteoporotic bone regeneration

Publication date: Available online 12 August 2017 Source:Acta Biomaterialia Author(s): Lixia Mao, Lunguo Xia, Jiang Chang, Jiaqiang Liu, Lingyong Jiang, Chengtie Wu, Bing Fang Abstracts Bioactive ions released from bioceramics play important roles in bone regeneration; h ... mehr

The influence of yttrium-segregation-dependent phase partitioning and residual stresses on the aging and fracture behaviour of 3Y-TZP ceramics

Publication date: Available online 12 August 2017 Source:Acta Biomaterialia Author(s): Dušan Bučevac, Tomaž Kosmač, Andraž Kocjan The yttrium-segregation-dependent phase partitioning and residual stress development that influence both the aging and the fracture behaviour in 3Y-T ... mehr

Self-defensive antibiotic-loaded layer-by-layer coatings: imaging of localized bacterial acidification and pH-triggering of antibiotic release

Publication date: Available online 9 August 2017 Source:Acta Biomaterialia Author(s): Victoria Albright, Iryna Zhuk, Yuhao Wang, Victor Selin, Betsy van de Belt-Gritter, Henk J. Busscher, Henny C. van der Mei, Svetlana Sukhishvili Self-defensive antibiotic-loaded coati ... mehr

Alle Fachpublikationen zu Biotechnologie

Fetal isovolumetric time intervals as a marker of abnormal cardiac function in fetal anemia from homozygous alpha thalassemia‐1 disease

Abstract Objective To determine whether fetal isovolumetric time intervals can be an early sonographic marker of fetal anemia in fetuses with homozygous alpha thalassemia‐1. Methods Pregnancies at risk for fetal homozygous alpha thalassemia‐1 disease at 18‐22 weeks were recruite ... mehr

Fetoscopic tracheal occlusion for treatment of non‐isolated congenital diaphragmatic hernia

Abstract Fetoscopic endotracheal occlusion (FETO) is a prenatal treatment that may increase survival in severe congenital diaphragmatic hernia (CDH). In the U.S., FETO is offered for isolated severe left‐sided CDH in the context of an FDA approved feasibility study. FETO in non‐isolated ... mehr

Implications of fetoplacental mosaicism on cell‐free DNA testing for sex chromosome aneuploidies

ABSTRACT Objective The unique biological behavior of sex chromosomes has implications for cell‐free DNA (cfDNA) testing. Our purpose is to predict the i) false positive/negative rates (FPR/FNR) of cfDNA testing consequent to feto‐placental mosaicism for any sex chromosome anomaly (SCA) ... mehr

Issue Information

No abstract is available for this article. mehr

Prenatal influence of congenital heart defects on trajectories of cortical folding of the fetal brain using three‐dimensional ultrasound

Abstract Objective To investigate the prenatal influence of congenital heart defects (CHD) on trajectories of fetal cortical folding using three‐dimensional ultrasound (3D‐US). Method We included 20 CHD fetuses and 193 controls for studying the fetal brain at 22, 26 and 32 weeks ... mehr

Alle Fachpublikationen zu Diagnostik

Inside the USCAP Journals

Inside the USCAP Journals Laboratory Investigation 97, 888 (August 2017). doi:10.1038/labinvest.2017.68 mehr

A pathologist|[rsquo]|s perspective on induced pluripotent stem cells

A pathologist’s perspective on induced pluripotent stem cells Laboratory Investigation advance online publication, July 31 2017. doi:10.1038/labinvest.2017.81 Authors: Noriko Watanabe, Katherine E Santostefano, Anthony T Yachnis & Naohiro Terada mehr

Papillary renal cell carcinoma-derived chemerin, IL-8, and CXCL16 promote monocyte recruitment and differentiation into foam-cell macrophages

Papillary renal cell carcinoma-derived chemerin, IL-8, and CXCL16 promote monocyte recruitment and differentiation into foam-cell macrophages Laboratory Investigation advance online publication, July 31 2017. doi:10.1038/labinvest.2017.78 Authors: Krzysztof M Krawczyk, Helén N ... mehr

Malignant melanoma: from cause to cure

Malignant melanoma: from cause to cure Laboratory Investigation 97, 762 (July 2017). doi:10.1038/labinvest.2017.58 mehr

Malignant melanoma: from cause to cure

Malignant melanoma: from cause to cure Laboratory Investigation 97, 628 (June 2017). doi:10.1038/labinvest.2017.57 mehr

Alle Fachpublikationen zu Labortechnik

Solubility, volumetric and compressibility properties of acetaminophen in some aqueous solutions of choline based deep eutectic solvents at T=(288.15 to 318.15) K

Publication date: 15 November 2017 Source:European Journal of Pharmaceutical Sciences, Volume 109 Author(s): Hemayat Shekaari, Mohammed Taghi Zafarani-Moattar, Masumeh Mokhtarpour Deep eutectic solvents (DESs) as a new class of green solvents have been used to overcome the low s ... mehr

ERE-dependent transcription and cell proliferation: Independency of these two processes mediated by the introduction of a sulfone function into the weak estrogen estrothiazine

Publication date: 15 November 2017 Source:European Journal of Pharmaceutical Sciences, Volume 109 Author(s): Yves Jacquot, Dany Spaggiari, Julie Schappler, Eric Lesniewska, Serge Rudaz, Guy Leclercq The synthetic coumestrol derivative 6,12-dihydro-3-methoxy-1-benzopyrano[3 ... mehr

Calendar of Events

Publication date: 30 September 2017 Source:European Journal of Pharmaceutical Sciences, Volume 107 mehr

Co-encapsulation of paclitaxel and C6 ceramide in tributyrin-containing nanocarriers improve co-localization in the skin and potentiate cytotoxic effects in 2D and 3D models

Publication date: 15 November 2017 Source:European Journal of Pharmaceutical Sciences, Volume 109 Author(s): Vanessa F.M. Carvalho, Amanda Migotto, Daniela V. Giacone, Débora P. de Lemos, Thalita B. Zanoni, Silvya S. Maria-Engler, Leticia V. Costa-Lotufo, Luciana B. Lo ... mehr

Melanin binding study of clinical drugs with cassette dosing and rapid equilibrium dialysis inserts

Publication date: 15 November 2017 Source:European Journal of Pharmaceutical Sciences, Volume 109 Author(s): Laura Pelkonen, Unni Tengvall-Unadike, Marika Ruponen, Heidi Kidron, Eva M. del Amo, Mika Reinisalo, Arto Urtti Melanin pigment is a negatively charged polymer fo ... mehr

Alle Fachpublikationen zu Pharma

A novel BCMA|[sol]|CD3 bispecific T-cell engager for the treatment of multiple myeloma induces selective lysis in vitro and in vivo

A novel BCMA/CD3 bispecific T-cell engager for the treatment of multiple myeloma induces selective lysis in vitro and in vivo Leukemia advance online publication, January 13 2017. doi:10.1038/leu.2016.388 Authors: S Hipp, Y-T Tai, D Blanset, P Deegen, J Wahl, O Thomas, B Ratte ... mehr

A TLR7 agonist enhances the antitumor efficacy of obinutuzumab in murine lymphoma models via NK cells and CD4 T cells

A TLR7 agonist enhances the antitumor efficacy of obinutuzumab in murine lymphoma models via NK cells and CD4 T cells Leukemia advance online publication, January 3 2017. doi:10.1038/leu.2016.352 Authors: E J Cheadle, G Lipowska-Bhalla, S J Dovedi, E Fagnano, C Klein, J Honeyc ... mehr

Masked hypertension|[mdash]|what lies ahead|[quest]|

Masked hypertension—what lies ahead? Journal of Human Hypertension 31, 545 (September 2017). doi:10.1038/jhh.2017.11 Authors: D E Anstey & D Shimbo mehr

Masked hypertension|[mdash]|what lies ahead|[quest]|

Masked hypertension—what lies ahead? Journal of Human Hypertension, Published online: 9 August 2017; doi:10.1038/jhh.2017.11 mehr

Discordant American College of Physicians and international rheumatology guidelines for gout management: consensus statement of the Gout, Hyperuricemia and Crystal-Associated D ...

Nature Reviews Rheumatology. doi:10.1038/nrrheum.2017.126 Authors: Nicola Dalbeth, Thomas Bardin, Michael Doherty, Frédéric Lioté, Pascal Richette, Kenneth G. Saag, Alexander K. So, Lisa K. Stamp, Hyon K. Choi & Robert Terkeltaub mehr

Alle Fachpublikationen zu Medizin
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