 |
|
|
|
 |
|
|
Article 1 - 5 of 8 |
|
Quality control of colorimetrically stained gels and blots
Comparison of 2 methods
In the pharmaceutical and food industry, using a scanner-based system is more recommended than using a camera-based system for the acquisition, documentation and analysis of colorimetrically stained gels, blots and TLC samples. The combination of a scanner with a suitable control and analysis software is decisively for completely meeting GxP guidelines...
|
|
Characterization of micelles and liposomes using the Eclipse 3+ AF4 separation system coupled to a DAWN HELEOS II MALS detector
Micelles and liposomes can serve as vehicles used to solubilize and carry bioactive compounds to their site of action, thus increasing their bioavailability. First experience has been made using vitamins and enzymes as functional food additives. Moreover, micelles could be useful to deliver drugs to a defined site of action, thus reducing frequently occurring side effects of systemic drug administration. Micelles are true nano-materials with a size range of 10 to 30 nm in diameter. Ideally, they should have a narrow size distribution. Furthermore, they have to be stable and should release their active compound only in the target region. Characterization of the micelle suspensions is vital to guarantee these properties and has to cover several aspects. One important point is size distribution, which has to be determined with high resolution...
|
|
|
|
Do you see the complete picture?
"Triple Detection" in Gel Permeation Chromatography
Gel permeation chromatography (GPC) or also named size exclusion chromatography (SEC) is the most often used method for determining the molecular weight of natural and synthetic macromolecules. One specific strength of this method lies in the fact that by the separation process the whole molecular weight distribution is obtained. The molecular weight distribution contains much larger information for the characterization of polymer samples compared to a single value....
|
|
Half a Century of Chromatography with Agilent and Predecessors
One Century of Chromatography with Twsett (1903)
Twsett originated the chromatography with his work about the separation of chlorophyll in 1903. For some time it was relatively quite around this new technology. Exceptions were the workings of Kuhn and Lederer (1931) as well as of Hesse (1936 and 1942). A break through succeeded to E. Cremer during the 40ies, but hardly considered caused by the war events, what however in the years 1950/51 by the conception of the gas chromatography suddenly changed and involved a rapid development...
|
|
|
|
|
|
|
|
Top
